MATERIALS AND METHODS: We retrospectively analyzed twenty-two patients of ADPKD with renal calculi managed by percutaneous nephrolithtomy (PCNL) from January 2000 to January 2010. Patients were divided into two groups: group I (serum creatinine ≤ 1.5 mg%), group II (serum creatinine >1.5 mg%).
RESULTS: PCNL was done in 25 renal units among 22 patients. Sixteen patients had chronic kidney disease, and the average stone burden was 2.4 cm ± 0.8 cm. The overall success rate (complete stone clearance/residual fragments < 4 mm) was 88% (22/25). Two patients required relook PCNL for residual stone and one required ESWL for the incomplete clearance. Mean preoperative serum creatinine in group I was 0.9 ± 0.1 mg% and in group II 3.1 ± 1.2 mg%. There was improvement in serum creatinine in group II (1.4 ± 0.5 mg%) postoperatively. Three patients required blood transfusion (13%) and four patients had fever postoperatively (18%). None of the patients required angioembolization.
CONCLUSION: Despite the distorted calyceal anatomy and associated chronic kidney disease, PCNL is safe and effective in managing nephrolithiasis in polycystic kidney disease.
Written by:
Srivastava A, Bansal R, Srivastava A, Chaturvedi S, Ranjan P, Ansari MS, Yadav A, Kapoor R. Are you the author?
Department of Urology and Renal Transplant, SGPGIMS, Lucknow, India.
Reference: Int Urol Nephrol. 2011 Nov 20. Epub ahead of print.
doi: 10.1007/s11255-011-0090-z
PubMed Abstract
PMID: 22102138
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