Chemohormonal Therapy vs. Hormonal Therapy for Hormone-sensitive - Results from #10

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Managing Urinary Incontinence in Dementia Patients: External Collection Devices and Absorbent Products - Diane Newman Details Diane Newman addresses the complexities of managing urinary incontinence in bedbound or non-mobile individuals, particularly within the elderly population. Highlighting that a complete cure is often not feasible, she focuses on management strategies to enhance quality of life. Dr. Newman introduces various external collection devices, such as condom catheters for men, which minimize infection risk...
Overcoming Environmental Barriers to Incontinence Management in Dementia Patients - Diane Newman Details Diane Newman addresses managing incontinence in individuals with dementia, focusing on the unique challenges faced by this population. People with dementia often cannot recognize the need to use the restroom or how to use incontinence products correctly, leading to distress for both the individual and their caregivers. Dr. Newman suggests practical environmental adjustments to aid recognition and...
Understanding Urinary Incontinence in Older Adults: Anatomy, Types, and Risk Factors - Diane Newman Details Diane Newman delves into the complexities of managing incontinence, particularly in individuals with dementia. She begins by elucidating the anatomy and function of the bladder, emphasizing its role in the urinary tract and how it is affected by neurological changes in older adults. Newman describes different types of incontinence, such as stress and urgency incontinence, explaining their causes a...
VA BRAVO 2 Study: Blue Light Cystoscopy Improves Outcomes in NMIBC Patients in Equal Access Setting - Stephen Williams Details Ashish Kamat introduces Stephen Williams who discusses findings from his study on blue light cystoscopy in bladder cancer treatment, conducted within the VA healthcare system. The study utilized a propensity score-matched analysis to compare the outcomes of blue light versus white light cystoscopy, focusing on bladder cancer recurrence, progression, and overall survival. The analysis revealed sign...
Evaluating a Sequential Screening Approach for Prostate Cancer Using PSA, Kallikrein Panel, and MRI in the ProScreen Trial, Journal Club - Rashid Sayyid & Zachary Klaassen Details Rashid Sayyid and Zach Klaassen explore the findings of the ProScreen trial, a rigorous examination into sequential prostate cancer screening using PSA, a kallikrein panel, and MRI. Highlighting the study's aim to refine screening methods by enhancing detection rates of high-grade cancers while reducing unnecessary diagnoses of low-grade conditions, they delve into the process and preliminary resu...
Value-Based Payment Models and Management of Newly Diagnosed Prostate Cancer - Avinash Maganty Details Ruchika Talwar welcomes Avinash Maganty to discuss research on value-based payment models in prostate cancer management, published in Cancer Medicine. Dr. Maganty explains that following the MACRA initiative of 2017, urologists had to adapt to payment models like MIPS and accountable care organizations, which potentially influence treatment decisions, especially in discretionary cases like low-gra...
SunRISe-3 Trial: TAR-200 with or without Cetrelimab vs. BCG for BCG-Naive High-Risk NMIBC - Sam Chang Details Ashish Kamat hosts Sam Chang to discuss the SunRISe-3 trial. Dr. Chang presents the ongoing trial investigating the efficacy of TAR-200, either alone or combined with cetrelimab, against BCG in treating patients with BCG-naive bladder cancer. TAR-200, a targeted release system using gemcitabine, is tested for its potential benefits over traditional treatments due to its unique delivery system aime...
EV-302 Subgroup Analyses: Enfortumab Vedotin + Pembrolizumab Effective Across Patient Subsets in Metastatic Urothelial Cancer - Jonathan Rosenberg Details Alicia Morgans introduces Jonathan Rosenberg who discusses the EV-302 trial. This Phase III trial, which Dr. Rosenberg explains, involved a comparison between enfortumab vedotin (EV) combined with pembrolizumab and traditional chemotherapy for untreated metastatic urothelial cancer patients. The results were striking, with a notable improvement in both progression-free and overall survival for pat...
PEACE V (STORM) Trial: Comparing MDT vs. Elective Nodal Irradiation for Oligorecurrent Prostate Cancer - Thomas Zilli Details Alicia Morgans interviews Thomas Zilli about the PEACE V study. The study, termed the STORM trial, investigates treatment strategies for patients with oligorecurrent prostate cancer, comparing focalized SBRT, comprehensive irradiation, and salvage lymph node dissection combined with six months of ADT. Aimed at determining the best approach for these patients, the trial specifically looks at metast...
Urology Program Directors Rank Letters of Recommendation as Top Factor in Residency Applications Post-USMLE Step 1 Change - Angeline Johny & Wesley Mayer Details Ruchika Talwar hosts Angeline Johny and Wesley to discuss the implications of the USMLE Step 1 exam's shift to a pass/fail format on residency applications in urology. They examine the growing need for objective measures in the application process amidst increasing application volumes and the fading of traditional metrics like class rank and detailed clerkship grades. Their study, utilizing a surv...