Clinical Trials

13 results for Bladder Cancer


A Phase II Clinical Trial to Study the Efficacy and Safety of Pembrolizumab (MK-3475) in Subjects With High Risk Non-muscle Invasive Bladder Cancer (NMIBC) Unresponsive to Bacillus Calmette-Guerin (BCG) Therapy

  • Condition: Bladder Cancer
  • Intervention: Biological: pembrolizumab
  • Study ID: NCT02625961
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A Phase 2, Randomized, Open-label Study of Nivolumab or Nivolumab/BMS-986205 Alone or Combined With Intravesical BCG in Participants With BCG-Unresponsive, High-Risk, Non-Muscle Invasive Bladder Cancer

  • Condition: Bladder Cancer, Bladder Tumors, Neoplasms, Bladder
  • Intervention: Biological: Nivolumab, Biological: BCG, Drug: BMS-986205
  • Study ID: NCT03519256
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PhAse 1/2 StuDy of Modern ImmunotherApy in BCG-RelaPsing UroThelial Carcinoma of the BLADDER - (ADAPT-BLADDER) HCRN GU16-243

  • Condition: Urothelial Carcinoma, Bladder Cancer
  • Intervention: Drug: Durvalumab, Radiation: External Beam Radiotherapy (EBRT), Biological: Bacillus Calmette-Guérin (BCG)
  • Study ID: NCT03317158
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Phase II Study of Pembrolizumab (MK-3475) as First-Line Therapy for High Risk T1 Non-Muscle-Invasive Bladder Cancer

  • Condition: Bladder Cancer
  • Intervention: Drug: Pembrolizumab (MK-3475)
  • Study ID: NCT03504163
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QUILT-3.032: A Multicenter Clinical Trial of Intravesical Bacillus Calmette-Guerin (BCG) in Combination With ALT-803 in Patients With BCG Unresponsive High Grade Non-Muscle Invasive Bladder Cancer

  • Condition: Bladder Cancer
  • Intervention: Drug: ALT-803, Drug: BCG
  • Study ID: NCT03022825
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An Open Label, Randomized, Phase III Trial, Evaluating Efficacy of Atezolizumab in Addition to One Year BCG (Bacillus CaLmette-Guerin) Bladder Instillation in BCG-naive Patients With High-risk Non-muscle Invasive Bladder cANcer

  • Condition: Bladder Cancer
  • Intervention: Drug: BCG, Drug: Atezolizumab
  • Study ID: NCT03799835
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Intravesical Mistletoe Extract in Superficial Bladder Cancer: A Phase III Efficacy Study

  • Condition: Superficial Bladder Cancer
  • Intervention: Drug: abnobaVISCUM 900, Drug: Mitomycin C
  • Study ID: NCT02106572
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Phase I Safety and Tolerability of Intravesical VAX014 for Instillation in Subjects With Non-Muscle Invasive Bladder Cancer (NMIBC)

  • Condition: Urothelial Carcinoma of the Urinary Bladder
  • Intervention: Drug: VAX014
  • Study ID: NCT03854721
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Intravesical Instillation Therapy With Bacillus Calmette-Guérin (BCG) and Sequential BCG and Electromotive Mitomycin-C (EMDA-MCC) in Patients With High-risk Non-muscle-invasive Bladder Carcinoma

  • Condition: Bladder Cancer
  • Intervention: Drug: BCG instillation therapy, Drug: Sequential BCG and EMDA mitomycin C
  • Study ID: NCT03664869
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Phase II Trial of Intravesical Gemcitabine and MK-3475 (Pembrolizumab) in the Treatment of Patients With BCG-Unresponsive Non-Muscle Invasive Bladder Cancer

  • Condition: Bladder Urothelial Carcinoma In Situ, High-Risk, Non-Muscle Invasive Bladder Urothelial Carcinoma, Infiltrating Bladder Mixed Carcinoma, Stage 0a Bladder Cancer AJCC v8, Stage 0is Bladder Cancer AJCC v8, Stage I Bladder Cancer AJCC v8
  • Intervention: Drug: Gemcitabine, Drug: Gemcitabine Hydrochloride, Biological: Pembrolizumab
  • Study ID: NCT04164082
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A Phase II Clinical Study of Intravesical Photodynamic Therapy in Patients With BCG-Unresponsive Non-Muscle Invasive Bladder Cancer ("NMIBC") Or Patients Who Are Intolerant to BCG Therapy ("Study").

  • Condition: Non-Muscle Invasive Bladder Cancer (NMIBC) Refractory to BCG
  • Intervention: Combination Product: TLD-1433 Bladder infusion and Photodynamic Therapy
  • Study ID: NCT03945162
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A Randomized Phase 2 Study of Erdafitinib Versus Investigator Choice of Intravesical Chemotherapy in Subjects Who Received Bacillus Calmette-Guérin (BCG) and Recurred With High Risk Non-Muscle-Invasive Bladder Cancer (NMIBC) and FGFR Mutations or Fusions

  • Condition: Urinary Bladder Neoplasms
  • Intervention: Drug: Erdafitinib, Drug: Investigator Choice (Gemcitabine), Drug: Investigator Choice (Mitomycin C)
  • Study ID: NCT04172675
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A Randomized, Controlled, Open-Label Study of the Efficacy, Durability, and Safety of UGN-102 With or Without TURBT in Patients With Low Grade Intermediate Risk Non-Muscle-Invasive Bladder Cancer (LG IR NMIBC)

  • Condition: Bladder Cancer, Urothelial Carcinoma, Urothelial Carcinoma Bladder
  • Study ID: NCT04688931
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