SUO 2017: Analysis Defining Optimal Management of Clinical Stage 1 High-Risk Nonseminomatous Germ Cell Testicular Cancer
Washington, DC (UroToday.com) The standard of care for clinical stage non-seminomatous germ cell testicular cancer (NSGCT) is active surveillance, single dose chemotherapy (BEP x 1) or primary RPLND. While most favor active surveillance for all CS1 NSGCT, some centers favor a risk stratification approach. For patients with high-risk features, such as presence of lymphovascular invasion (LVI), they would favor BEP x 1 rather than AS. However, there are good arguments for and against both approaches.
SUO 2017: Benefits of Alvimopan in Men Undergoing Retroperitoneal Lymph Node Dissection
Washington, DC (UroToday.com) With an increasing emphasis on improving post-operative courses after major operations, the ERAS pathway has been enthusiastically taken up by the bladder cancer community. However, a key component of the ERAS pathway is the use of pre-operative alvimopan (Entereg), a mu-receptor opioid antagonist. Having demonstrated efficacy in GI surgery and the radical cystectomy literature at reducing hospital length of stay and postoperative morbidity, the authors from this study assessed its utility following RPLND for testicular cancer.
SUO 2017: Testicular Cancer And Surveillance: Impact On Patient Anxiety Over Time, The Princess Margaret Cancer Centre Experience
Washington, DC (UroToday.com) Introduction: Surveillance has become a standard of care for stage 1 testicular cancer. However, little is known about its effects on anxiety and mental health. With some centers advocating adjuvant therapy for higher risk stage I disease, partially on the basis of patient anxiety, a better understanding of patients’ response to surveillance is required.
SUO 2017: Impact of Hospital Case Volume on Testicular Cancer Outcomes and Practice Patterns
Washington, DC (UroToday.com) Dr. Woldu and colleagues presented their results of a study assessing the impact of hospital case volume on testicular cancer outcomes. For other complex procedures, for example abdominal aortic aneurysm repair, Whipple procedure and radical cystectomy, there has been a call for centralization of these procedures to tertiary centers of excellence. Given the rarity of testicular germ cell tumors (TGCTs) and the complex aspects of management, the objective of this study was to evaluate the impact of hospital TGCT case volume on overall survival (OS) outcomes and practice patterns.