SUFU 2019: The Clinique Pasteur Score for Screening of Severe Obstructive Apnea Syndrome in Patients Presented with Nocturnal Polyuria

Miami, FL ( A study was conducted to evaluate a link between nocturnal polyuria and severe obstructive sleep apnea syndrome (OSAS). Researchers aimed to develop a novel test to identify severe OSAS in nocturic patients.

First, frequency volume charts were analyzed for the signs of nocturnal polyuria for all patients who were diagnosed with nocturia during 24-month period.  Once such participants were identified, they were sent to the sleep specialist who collected data on subjects’ age, BMI, morning headache, snoring, daytime sleepiness and apnea-hypopnea index (AHI). Study participants were categorized to severe, mild and moderate OSAS groups based on AHI score. AHI of 30 or more was considered severe.

A total number of 127 patients were enrolled in the study. One hundred and thirteen of them (89%) had severe OSAS. Data analysis identifies three primary predictive factors of OSAS development: age, gender, and BMI (Figure 1).

Figure 1
SUFU WM 2019 predictive factors of OSAS development

The Clinique Pasteur score was developed based on these findings. According to the presenter, patients who score ≥7 are recommended a referral to the sleep specialist
(Figure 2). Follow up studies will help to establish the validity of a novel score test on the population with nocturia.

Figure 2
SUFU WM 2019 population with nocturia

Presented by: Benoit Peyronnet, MD, The University of Rennes, France

Written by: Hanna Stambakio, BS, Clinical Research Coordinator, Division of Urology, University of Pennsylvania, Twitter: @AStambakio at the Society of Urodynamics, Female Pelvic Medicine & Urogenital Reconstruction Winter Meeting, SUFU 2019, February 26 - March 2, 2019, Miami, Florida