SIU 2017: Upper Tract Urothelial Carcinoma
Lisbon, Portugal (UroToday.com) Dr. Catto gave an excellent talk on the etiological factor for upper tract urothelial carcinoma (UTUC). This is a pan urothelial disease, which can be multifocal and consists of 1-5% of all urothelial carcinomas. It is more common in the ureter than the renal pelvis, and smoking is the most common etiological factor. It has been shown that smoking increases risk of bladder cancer by an odds ratio (OR) of 3.22 (2.29-4.52), ureter by OR of 6.2 (2.04-18.81), and renal pelvis by OR of 5.91 (1.47-23.66).
SIU 2017: Towards Precision Medicine in Advanced Prostate Cancer
Lisbon, Portugal (UroToday.com) Dr. Beltran began her presentation asking how we should translate genomics and molecular biomarkers into clinical practice. She also asked when we should think about metastatic biopsy. In a study where 150 metastatic CRPC biopsies were performed, DNA alterations were found in 22%, with 8% having germ line mutations. This brings us to ask several important questions, including when to test and who? And what gene panel to use. Should we test all patients with mCRPC for DNA repair mutations? We need to understand the functional and prognostic role of the less common mutations as well. This will give us the answer to other questions, including whether we should screen for prostate cancer (PC) among family carriers, and what the optimal management of carriers with localized PC should be.
SIU 2017: Outcomes of Pathologic T3a Renal Cell Carcinoma Up-Staged from Small Renal Tumor: Emphasis on Partial Nephrectomy
Lisbon, Portugal (UroToday.com) The prognosis of pathologic T3a renal cell carcinoma (RCC) that is up-staged from a small renal tumor is controversial. The authors evaluated the prognosis of RCC patients who were postoperatively up-staged from clinical T1 to pathologic T3a.
SIU 2017: New Diagnostic Techniques in Cystoscopy
Lisbon, Portugal (UroToday.com) Dr. Paniero presented a detailed description of various diagnostic techniques in cystoscopy. He began by stating that the TURBT procedure is limited due to residual tumor that can be left, and a significant problem of under-staging in this procedure. Therefore, there is a genuine need to improve endoscopic technology in order to improve TURBT outcomes.
SIU 2017: Robotic Partial Nephrectomy for Complex Renal Lesions: Strategies for Success - A Multi-institutional Study
Lisbon, Portugal (UroToday.com) Due to their size, location and proximity to the hilum, some complex renal tumors may preclude a minimally invasive approach to nephron sparing surgery. The authors describe their technique of robotic partial nephrectomy for challenging complex renal tumors.
SIU 2017: Surgical Treatment of Renal Cell Carcinoma in Elderly Patients: Functional Outcomes and Perioperative Complications
Lisbon, Portugal (UroToday.com) In this study the authors aimed to evaluate renal function outcomes and perioperative complications in elderly patients with renal cell carcinoma (RCC) who underwent either radical (RN) or partial nephrectomy (PN) at a single institution.
SIU 2017: The Prognostic Impact of Postoperative Neutrophil to Lymphocyte Ratio on Survival Outcomes in Patients Treated with Radical Nephroureterectomy for Upper Urinary Tract Urothelial Carcinoma
Lisbon, Portugal (UroToday.com) The purpose of this study was to investigate the prognostic association of postoperative neutrophil to lymphocyte ratio (NLR) with survival outcomes in upper urinary tract urothelial carcinoma (UTUC).