In conclusion, IRPC patients represent a heterogenous patient group, which require sub-stratification. Surgery impacts on the natural history of IRPC and the long-term outcomes of surgery in this groups are in general excellent. However, patients with favorable disease characteristics might be spared radical treatment (at least initially), and could probably be monitored at first stage.
Figure 1: SPCG-4 trial demonstrating outcomes of younger men and those with intermediate risk prostate cancer:
Figure 2: PIVOT trial – comparing death from any cause and death from prostate cancer between patients treated with observation and those treated with Radical prostatectomy:
Speaker: Steven Joniau, MD, PhD, Associate Professor, Consultant Urologist Department of Urology University Hospitals Leuven, Belgium.
Written By: Hanan Goldberg, MD, Urologic Oncology Fellow (SUO), University of Toronto, Princess Margaret Cancer Centre @GoldbergHanan at The 15th Meeting of the EAU Section of Oncological Urology ESOU18 - January 26-28, 2018 - Amsterdam, The Netherlands
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