This was a retrospective study on 758 diabetic men undergoing primary PP placement across 17 institutions. Osman highlights that this is currently the largest database on diabetic patients with PP placement. Pre-operative serum blood glucose (PBG) and HbA1c levels were assessed, along with covariates of age, diabetes type, diabetes-related complications, BMI, prosthesis type, Charlson Comorbidity Index, history of immunosuppression and prior radical prostatectomy were evaluated as well. All variables were assessed for primary outcomes of post-operative infection, and secondary outcomes of revision and explantation rates.
They found that preoperative blood glucose and HbA1c levels were not predictive of postoperative infection, revision, or explanation rates. Additionally, no significant predictors were found in multivariate analysis in predicting risks of explanation and revision. However, Osman emphasized that they did find that on multivariate analysis, patients with a history of diabetes-related complications (neuropathy, retinopathy, etc.) are at an increased risk for postoperative infection by about 3 times.
Presented by: Mahdi Osman, MD, Researcher, Department of Urology, University of California-Irvine, Irvine, California
Written by: Kaelyn See, Department of Urology, University of California-Irvine, at the American Urological Association's 2019 Annual Meeting (AUA 2019), May 3 – 6, 2019 in Chicago, Illinois