- Short term follow-up of ablation patients. The median follow-up was 2.9 years for the radiofrequency patients and 1.4 years for the cryotherapy patients.
- Inconsistent definitions of local recurrence
- 27 ablation patients had no follow-up
- Clear selection bias
Table 1 – Baseline features of Mayo clinic patients:
No difference was noted in local recurrence-free survival, metastasis free survival, and cancer-specific survival (Figure 1).
Figure 1: - Local recurrence free survival, metastasis free survival, and cancer specific survival of patients undergoing PN and ablative treatments:
Ablative treatments are far from perfect and could lead to significant complications. These include bleeding with large perinephric hematomas, urine leaks leading to large urinomas, pseudoaneurysms and more.
Despite the disadvantages of ablative techniques, this is still an attractive minimally invasive technique, with good overall results, and relatively low complication rate, and should be utilized more commonly for SRM<3 cm.
Presented by: Houston Thompson, MD, Mayo Clinic, Rochester, MN, USA
1. Thompson Houston et al. Comparison of partial nephrectomy and percutaneous ablation for CT1 renal masses. European Urology 67 (2015) 252-259
Written by: Hanan Goldberg, MD, Urologic Oncology Fellow (SUO), University of Toronto, Princess Margaret Cancer Centre @GoldbergHanan at the 2018 AUA Annual Meeting - May 18 - 21, 2018 – San Francisco, CA USA
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Controversies in Urology: Kidney Cancer – Treatment with Thermal Ablation – PRO
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Controversies in Urology: Kidney Cancer – Treatment with Thermal Ablation – CON
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Controversies in Urology: Kidney Cancer – Treatment with Thermal Ablation – CON Rebuttal