AUA 2017: Impact of Metabolic Syndrome on the Occurrence of Premature Ejaculation

Boston, MA (UroToday.com) There is a known association between erectile dysfunction and metabolic syndrome (MetS). There are a few reports describing the relationship between premature ejaculation (PE) and MetS. Dr. Jeh presented a study investigating the effect of MetS in the pathogenesis of ejaculatory symptoms, and the risk factors associated with PE.

1,029 men who visited our clinic for male health screening between January 2010 and July 2014 were analyzed. Multivariate analyses included age, International Prostate Symptom Score (IPSS), International Index of Erectile Function (IIEF) score, National Institutes of Health-Chronic Prostatitis Symptom Index (NIH-CPSI) score, body mass index, Androgen Deficiency in the Aging Male (ADAM) score, serum testosterone levels, and all components of MetS. PE was defined as self-reported intravaginal ejaculation latency time (IELT) <1 minute, and MetS was diagnosed by using the modified National Cholesterol Education Program Adult Treatment Panel III (NCEP ATP III) criteria. Additionally, the Male Sexual Health Questionnaire for Ejaculatory Dysfunction (MSHQ-EjD) was used to analyze ejaculation anxiety.

The results showed that 74 (7.2%) had PE (ejaculation within 1 min) and 111 (10.8%) had MetS. Multivariate logistic regression analysis showed that IIEF overall satisfaction score, NIH-CPSI pain score, NIH-CPSI voiding score, and presence of MetS were significantly correlated with prevalence of PE. Additionally, MSHQ-EjD and ejaculation anxiety scores progressively decreased as the number of components of MetS increased.

To conclude, MetS may be an important factor predisposing the development of PE. Effective prevention and treatment of MetS could potentially be important for the prevention of PE.

Presented By: Seong Uk Jeh, Jinju, Korea, Republic of

Written By: Hanan Goldberg, MD, Urologic Oncology Fellow (SUO), University of Toronto, Princess Margaret Cancer Centre

at the 2017 AUA Annual Meeting - May 12 - 16, 2017 – Boston, Massachusetts, USA
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