AUA 2017: B-Mode Ultrasound Assessment of Penile Corporal Heterogeneity Correlates to Ultrafast™ Doppler Quantification of End Diastolic Velocity (EDV) in Men with Erectile Dysfunction (ED): Foundation for Algorithmic Assessment of Penile Fibrosis

Boston, MA (UroToday.com) Corporal fibrosis is a common etiology in patients with erectile dysfunction (ED). Among the available imaging modalities to evaluate ED, ultrasound (US) is used to measure the end diastolic velocity (EDV) of the penile corporal artery to characterize the extent and establish a threshold of disease. The US images themselves however, are not collected concurrently with EDV as data to more precisely evaluate the location and severity of corporal fibrosis. A group of urologists from San Diego collected a series of US images from patients with ED in an effort to create an imaging technique that systematically evaluates corporal fibrosis.

After reviewing 159 duplex Doppler studies of patients with ED (mean IIEF score, 13) a positive correlation was found between the heterogeneity of the erectile tissue on US and the absolute value of EDV. Importantly, they suggested that US can be used to identify ED early on in the disease process. Dr. Winter, on behalf of her colleagues, spoke passionately of the use-value of the US images and their place as clinical indicators of the presence and extent of corporal fibrosis in ED. She commented that additional prospective and randomized studies will be required to quantify fibrosis severity and create a technique that is user friendly for urologists and radiological technicians incorporating penile tissue heterogeneity into the diagnosis or follow-up of ED.

Presented By: Ashley G. Winter, MD

Authors: Rachel S. Rubin1,2, Ashley G. Winter1,2, Irwin Goldstein1

Affiliation: 1San Diego Sexual Medicine, 2Kaiser Permanente San Diego

Written By: Daniel Lama for UroToday.com

at the 2017 AUA Annual Meeting - May 12 - 16, 2017 – Boston, Massachusetts, USA

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