To assess the PCa detection rates of contrast-enhanced, transrectal subharmonic ultrasound imaging (SHI).
This IRB-approved study enrolled 55 subjects. The initial 5 subjects were studied for SHI optimization, while the remaining 50 were evaluated with contrast-enhanced sonography using continuous SHI, color and power Doppler as well as conventional grayscale, continuous color and power Doppler and SHI combined with maximum flash replenishment.