Testicular Cancer

Genomic landscape of adult testicular germ cell tumours in the 100,000 Genomes Project.

Testicular germ cell tumours (TGCT), which comprise seminoma and non-seminoma subtypes, are the most common cancers in young men. In this study, we present a comprehensive whole genome sequencing analysis of adult TGCTs.

Management of Small Testicular Masses: A Delphi Consensus Study.

The majority of small testicular masses (STMs) are benign and therefore radical orchidectomy (RO) may represent overtreatment. In appropriately selected patients, surveillance or testis-sparing surgery (TSS) is an alternative option to preserve testicular function.

Radiological Assessment of Different Retroperitoneal Lymph Node Measurements in Stage 1 Testicular Cancer Patients: Impact on Clinical Stage and Treatment - Beyond the Abstract

This study was conducted at the Federal Armed Forces Hospital in Koblenz, Germany, following our survey from last year (published by UroToday on June 6, 2023). In that survey, we highlighted considerable discrepancies between international and national guidelines regarding the radiological measurement (plane and diameter) of retroperitoneal lymph node metastases in testicular cancer patients.

Diagnostic and prognostic role of NLR in testicular cancer.

To summarize the results of available studies for investigating the role of neutrophil to lymphocyte ratio (NLR) in testicular cancer (tCa).

The search was conducted on PubMed, Scopus, and Web of Science up to November 21, 2021.

Refractory testicular germ cell tumors are highly sensitive to the targeting of polycomb pathway demethylases KDM6A and KDM6B.

Testicular germ cell tumors (TGCTs) can be treated with cisplatin-based therapy. However, a clinically significant number of cisplatin-resistant patients die from progressive disease as no effective alternatives exist.

Chemokine Profile Is Different in Normal Testis Compared to Seminoma - Especially in Tumor Infiltrating Lymphocytes.

Testicular cancers, particularly seminomas and non-seminomas, generally have a favorable prognosis, although a small subset of patients experience mortality. Current knowledge of clinical markers associated with relapse and poor prognosis in seminoma is limited.

Young adult Latino testicular cancer survivors: a pilot study of Goal-focused Emotion regulation Therapy (GET).

Young adult Latino testicular cancer survivors experience adverse impacts after treatment. We developed Goal-focused Emotion regulation Therapy (GET) to improve distress symptoms, goal navigation skills, and emotion regulation.

Comorbidities in Japanese testicular cancer survivors: A multi-institutional, cross-sectional study.

To evaluate comorbidities in Japanese testicular cancer (TC) survivors in a multi-institutional, cross-sectional study.

This study enrolled TC survivors who visited any of the eight high-volume institutions in Japan from 2018 to 2019.

New tumor markers for testicular cancer - in the here and now and in the future.

Germ cell tumors of the testis are the most common tumor entities in young men. Since the introduction of platinum-based chemotherapy in the 1970s, most patients can be cured despite the aggressiveness of germ cell tumors.

The Utility of Immuno-Nutritional Scores in Patients with Testicular Germ Cell Tumors.

Hemoglobin, Albumin, Lymphocyte, and Platelet Score (HALP) is an accessible score that is easily reproducible from routine laboratory testing while also reflecting patients' immune-nutritional status.