Real-World Adjuvant Nivolumab in PD-L1 Positive Muscle-Invasive Urothelial Carcinoma - Aurea Molina Diaz
July 21, 2026
Aurea Molina Diaz discusses the PrInCIS-NIADY, a nationwide Spanish real-world study of adjuvant nivolumab in patients with high-risk PD-L1-positive muscle-invasive urothelial carcinoma following surgery. In nearly 400 patients with 13 months of median follow-up, the 18-month disease-free survival estimate was 65.6% and median disease-free survival had not yet been reached. The cohort was older than the CheckMate 274 population with approximately 75% of patients over age 65, and grade 3/4 adverse events were seen in only 1%.
Biographies:
Aurea Molina Diaz, MD, Medical Oncologist, Universidad Santiago de Compostela, Santiago, Spain
Zachary Klaassen, MD, MSc, Urologic Oncologist, Assistant Professor of Surgery/Urology at the Medical College of Georgia at Augusta University, Wellstar MCG, Georgia Cancer Center, Augusta, GA
Biographies:
Aurea Molina Diaz, MD, Medical Oncologist, Universidad Santiago de Compostela, Santiago, Spain
Zachary Klaassen, MD, MSc, Urologic Oncologist, Assistant Professor of Surgery/Urology at the Medical College of Georgia at Augusta University, Wellstar MCG, Georgia Cancer Center, Augusta, GA
Related Content:
ASCO 2026: Adjuvant Nivolumab in High-Risk Muscle-Invasive Urothelial Carcinoma: Real-World Evidence from the SOGUG-NIADY Study of the Spanish Oncology Genitourinary Group (SOGUG)
SUO 2025: Adjuvant Nivolumab versus Placebo for High-Risk Muscle Invasive Urothelial Carcinoma: 5-Year Follow-up Results from CheckMate-274 Including Exploratory Analyses for Muscle Invasive Bladder Cancer and ctDNA
ASCO GU 2025: Adjuvant Nivolumab vs Placebo for High-Risk Muscle-Invasive Urothelial Carcinoma: Additional Efficacy Outcomes Including Overall Survival in Patients with MIBC from CheckMate 274
ASCO 2026: Adjuvant Nivolumab in High-Risk Muscle-Invasive Urothelial Carcinoma: Real-World Evidence from the SOGUG-NIADY Study of the Spanish Oncology Genitourinary Group (SOGUG)
SUO 2025: Adjuvant Nivolumab versus Placebo for High-Risk Muscle Invasive Urothelial Carcinoma: 5-Year Follow-up Results from CheckMate-274 Including Exploratory Analyses for Muscle Invasive Bladder Cancer and ctDNA
ASCO GU 2025: Adjuvant Nivolumab vs Placebo for High-Risk Muscle-Invasive Urothelial Carcinoma: Additional Efficacy Outcomes Including Overall Survival in Patients with MIBC from CheckMate 274
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