Real-World Adjuvant Nivolumab in PD-L1 Positive Muscle-Invasive Urothelial Carcinoma - Aurea Molina Diaz

July 21, 2026

Aurea Molina Diaz discusses the PrInCIS-NIADY, a nationwide Spanish real-world study of adjuvant nivolumab in patients with high-risk PD-L1-positive muscle-invasive urothelial carcinoma following surgery. In nearly 400 patients with 13 months of median follow-up, the 18-month disease-free survival estimate was 65.6% and median disease-free survival had not yet been reached. The cohort was older than the CheckMate 274 population with approximately 75% of patients over age 65, and grade 3/4 adverse events were seen in only 1%.

Biographies:

Aurea Molina Diaz, MD, Medical Oncologist, Universidad Santiago de Compostela, Santiago, Spain

Zachary Klaassen, MD, MSc, Urologic Oncologist, Assistant Professor of Surgery/Urology at the Medical College of Georgia at Augusta University, Wellstar MCG, Georgia Cancer Center, Augusta, GA



Read the Full Video Transcript