This study aimed to compare the perioperative and oncologic outcomes between robotic and open retroperitoneal lymph node dissection in patients with testicular cancer.
The study was conducted in accordance with the PRISMA guidelines, and quality assessment was performed following the AMSTAR criteria. A systematic search was performed in Embase, PubMed, and Web of Science databases, with the search period up to July 2025. Statistical analysis was performed using Stata 17 software.
The current results showed that compared with open retroperitoneal lymph node dissection (O-RLND), robotic retroperitoneal lymph node dissection (R-RPLND) had a shorter hospital length of stay (effect, - 3.68; 95 % confidence interval [CI], - 4.16 to - 3.21; P < 0.05), less estimated blood loss (effect, - 296.09; 95 % CI, - 416.62 to - 175.55; P < 0.05), and a lower overall complication rate (relative risk, 0.66; 95 % CI, 0.49-0.89; P < 0.05). Lymph node production and recurrence rate did not differ significantly between the two.
Robotic retroperitoneal lymph node dissection appears to be safer than O-RLND and has a faster postoperative recovery. Oncologic outcomes did not differ significantly, but more research is needed to explore further.
Annals of surgical oncology. 2026 Apr 02 [Epub ahead of print]
Pan Zhao, Xiaojun Tan, Ye Xie, Ran Deng, Fang Peng
Department of Urology, Nanchong Central Hospital, The Second Clinical College, North Sichuan Medical College (University), Nanchong, Sichuan, China. ., Department of Urology, Nanchong Central Hospital, The Second Clinical College, North Sichuan Medical College (University), Nanchong, Sichuan, China., Department of Otolaryngology, Nanchong Central Hospital, The Second Clinical College, North Sichuan Medical College (University), Nanchong, Sichuan, China.