While the benefits of physical activity (PA) for cancer survivors are well-documented, there is limited research specifically exploring its effects on health-related quality of life (HRQoL) among testicular cancer (TC) survivors.
This review aims to examine the available literature on the relationship between PA and HRQoL in TC survivors post-treatment.
To identify and synthesize existing studies on the effects of PA on HRQoL outcomes in TC survivors.
Studies that examined the relationship between PA, TC survivorship, and HRQoL across various phases of survivorship were included. Only peer-reviewed articles and gray literature addressing these topics were considered.
A systematic search was conducted across seven databases and gray literature. Articles were evaluated based on titles, abstracts, and full-text reviews for inclusion.
Following Arksey and O'Malley's scoping review framework and PRISMA-ScR guidelines, studies were charted for key findings regarding the effects of PA on cancer-related fatigue, psychosocial outcomes, and HRQoL in TC survivors. The search also focused on identifying barriers to PA adherence and gaps in the current literature.
Three studies were examined: one experimental study, one feasibility study, and one cross-sectional study. Findings suggested that PA interventions could reduce cancer-related fatigue, improve psychosocial well-being, and enhance HRQoL indicators such as vitality, self-esteem, and social functioning. High-intensity interval training showed short-term benefits, while low-intensity activities demonstrated feasibility for broader adoption. Adherence barriers included treatment side effects and psychosocial factors. Limitations included small sample sizes, self-reported data, and lack of long-term follow-up.
The findings suggest that PA can improve HRQoL in TC survivors, but significant gaps remain, particularly in terms of longitudinal studies, diverse populations, and tailored interventions. Future research should focus on developing scalable, sustainable PA interventions that address adherence and long-term health outcomes for TC survivors.
A review of evidence between physical activity and testicular cancer A scoping review was conducted to understand the breadth and depth of available literature on the relationship between testicular cancer survivorship and if physical activity can have a net-positive benefit to patient-reported post-treatment outcomes. Overall, the studies indicated a positive net effect of physical activity and testicular cancer survivorship patient-reported outcomes, particularly around the increased perceived need for exercise, reduced cancer-related fatigue, and a lessening of anxiety and depressive symptoms.
Therapeutic advances in urology. 2025 Feb 25*** epublish ***
Michael J Rovito, Keith Brazendale, Samantha Gibson, Sydney Martinez, Ciaran Fairman, Craig Badolato, Timothy Lyon, Bryce Baird, Jaclyn Langan, M K Leslie
University of Central Florida, 4364 Scorpius Street, HPA2-210K, Orlando, FL 32816, USA., Department of Health Sciences, University of Central Florida, Orlando, FL, USA., Department of Exercise Science, University of South Carolina, Columbia, SC, USA., Cancer Care Centers of Brevard, Melbourne, FL, USA., The Mayo Clinic, Rochester, MN, USA.
PubMed http://www.ncbi.nlm.nih.gov/pubmed/40012558