Screening programs for prostate cancer based on the determination of serum prostate specific antigen has led to overdiagnosis, and consequently overtreatment. A percentage of men diagnosed with prostate cancer have a tumour that will not progress, or do so slowly (overdiagnosis or pseudo-disease). This overdiagnosis rate ranges from 17-50%. Mass screening is defined as the systematic examination of asymptomatic men. Early detection or opportunistic screening involves the pursuit of individual cases being initiated by the doctor or the patient. In the case of a patient who requests a prostate specific antigen from their general practitioner, a number of issues on overdiagnosis, over-treatment and possible damage from the biopsy, should be explained to him. With data from randomised studies on prostate specific antigen and prostate cancer screening, population screening is not recommended by any urological society.
Semergen / Sociedad Espanola de Medicina Rural y Generalista. 2016 Aug 22 [Epub ahead of print]
A Jalón Monzón, S Escaf Barmadah, L M Viña Alonso, M Jalón Monzón
Servicio de Urología, Hospital Universitario Central de Asturias (HUCA), Oviedo, Asturias, España. Electronic address: ., Servicio de Urología, Hospital Universitario Central de Asturias (HUCA), Oviedo, Asturias, España., Centro de Salud El Parque-Somió, Gijón, Asturias, España., Centro de Salud de Contrueces, Gijón, Asturias, España.