Current treatment of metastatic bone prostate cancer with Docetaxel chemotherapy per CHAARTED trial is standard of care. Timing of CT and bone scintigraphy for evaluation of successful treatment of lytic lesions is not available in the literature. We present a case of a 70 year old male with PSA of 586 and wide spread metastatic bone lytic lesions, who underwent androgen deprivation therapy and six cycles of Docetaxel chemotherapy. The patient had clinically successful treatment. Contrast enhanced CT scan demonstrated sclerotic bone lesions with PSA 2.5 at this point in treatment; however, 99mTc-MDP bone scintigraphy remained positive for metastatic lesions.
Urology case reports. 2016 Feb 22*** epublish ***
Victoria Yvonne Bird, Paula M Domino, Raymond Sutkowski, Stephanie A Stillings, Jorge A Trejo-Lopez
University of Florida, Gainesville, Florida, United States., University of Florida, Department of Urology, United States., University of Florida, Department of Radiology, United States., University of Florida, School of Medicine, United States., University of Florida, Department of Pathology, United States.