To compare rates of 30-day post-operative complications after transurethral resection of bladder tumors (TURBT) in octogenarians versus younger patients.
We conducted a review of the NSQIP database from 2012 to 2022.
We included patients undergoing TURBT as the principal procedure, and excluded patients with disseminated cancer, pre-operative sepsis, or who were ventilator-dependent. We conducted multivariate logistic regression modeling to evaluate the association of age (≥ 80 vs. < 80 years) with 30-day post-operative complications, adjusting for confounders. We report adjusted odds ratios (aOR) and 95% confidence intervals (CI).
We identified 78,665 reports of TURBT, of which 21,627 (27.5%) were performed on patients aged ≥ 80. In multivariate analysis, age ≥ 80 was significantly associated with septic shock (aOR 2.29; 95% CI 1.44-3.66), receipt of blood transfusion ≤ 72 h (aOR 1.42; 95% CI 1.20-1.67), prolonged post-operative stay ≥ 1 day (aOR 1.50; 95% CI 1.43-1.57), unplanned related readmission (aOR 1.26; 95% CI 1.15-1.38), and death (aOR 2.74; 95% CI 2.15-3.52). Octogenarians had greater rates of readmission for hematuria (0.7% vs. 0.5%) but not reoperation for hematuria (0.7% vs. 0.8%). Octogenarians were also more frequently readmitted for severe complications (31.8% vs. 26.3% CD grades 3-5).
Octogenarians who underwent TURBT experienced higher rates of several serious 30-day complications. While TURBT in octogenarians has a low rate of complications overall, clinicians should remain mindful of increased risk of complications for pre-operative counseling and discharge preparation.
World journal of urology. 2025 Nov 24*** epublish ***
Jonathan J Song, Maya T Zhou, Samuel Z Lee, James McAndrew Jones, Mark H Katz, David S Wang
Boston University Chobanian and Avedisian School of Medicine, Boston, MA, USA., Department of Urology, Boston Medical Center, 725 Albany Street, Suite 3B, Boston, MA, 02118, USA., Department of Urology, Boston Medical Center, 725 Albany Street, Suite 3B, Boston, MA, 02118, USA. .
PubMed http://www.ncbi.nlm.nih.gov/pubmed/41284039