Role of multiparametric magnetic resonance imaging in the diagnosis and staging of urinary bladder cancer.

To assess the role of multiparametric magnetic resonance imaging (mp-MRI) in the diagnosis and staging of urinary bladder cancer (BC).

Fifty patients diagnosed with bladder masses underwent mp-MRI study.

The results of 3 image sets were analyzed and compared with the histopathological results as a reference standard: T2-weighted image (T2WI) plus dynamic contrast-enhanced (DCE), T2WI plus diffusion-weighted images (DWI), and mp-MRI, including T2WI plus DWI and DCE. The diagnostic accuracy of mp-MRI was evaluated using receiver operating characteristic curve analysis.

The accuracy of T2WI plus DCE for detecting muscle invasion of BC was 79.5% with a fair agreement with histopathological examination (κ = 0.59); this percentage increased up to 88.6% using T2WI plus DWI, with good agreement with histopathological examination (κ = 0.74), whereas mp-MRI had the highest overall accuracy (95.4%) and excellent agreement with histopathological data (κ = 0.83). Multiparametric MRI can differentiate between low- and high-grade bladder tumors with a high sensitivity and specificity of 93.3% and 98.3%, respectively.

Multiparametric MRI is an acceptable method for the preoperative detection and accurate staging of BC, with reasonable accuracy in differentiating between low- and high-grade BC.

Current urology. 2022 Aug 31 [Epub]

Essam A Shalaby, Ahmed R Mohamed, Tarek H Elkammash, Rasha T Abouelkheir, Ahmed M Housseini

Department of Urology, Faculty of Medicine, Suez Canal University, Ismailia, Egypt., Department of Diagnostic Radiology, Faculty of Medicine, Suez Canal University, Ismailia, Egypt., Diagnostic Radiology, Urology and Nephrology Center, Mansura University, Mansura, Egypt.

Read an Expert Commentary by Bishoy Faltas, MD

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