Computerized Decision Support for Bladder Cancer Treatment Response Assessment in CT Urography: Effect on Diagnostic Accuracy in Multi-Institution Multi-Specialty Study.

This observer study investigates the effect of computerized artificial intelligence (AI)-based decision support system (CDSS-T) on physicians' diagnostic accuracy in assessing bladder cancer treatment response. The performance of 17 observers was evaluated when assessing bladder cancer treatment response without and with CDSS-T using pre- and post-chemotherapy CTU scans in 123 patients having 157 pre- and post-treatment cancer pairs. The impact of cancer case difficulty, observers' clinical experience, institution affiliation, specialty, and the assessment times on the observers' diagnostic performance with and without using CDSS-T were analyzed. It was found that the average performance of the 17 observers was significantly improved (p = 0.002) when aided by the CDSS-T. The cancer case difficulty, institution affiliation, specialty, and the assessment times influenced the observers' performance without CDSS-T. The AI-based decision support system has the potential to improve the diagnostic accuracy in assessing bladder cancer treatment response and result in more consistent performance among all physicians.

Tomography (Ann Arbor, Mich.). 2022 Mar 02*** epublish ***

Di Sun, Lubomir Hadjiiski, Ajjai Alva, Yousef Zakharia, Monika Joshi, Heang-Ping Chan, Rohan Garje, Lauren Pomerantz, Dean Elhag, Richard H Cohan, Elaine M Caoili, Wesley T Kerr, Kenny H Cha, Galina Kirova-Nedyalkova, Matthew S Davenport, Prasad R Shankar, Isaac R Francis, Kimberly Shampain, Nathaniel Meyer, Daniel Barkmeier, Sean Woolen, Phillip L Palmbos, Alon Z Weizer, Ravi K Samala, Chuan Zhou, Martha Matuszak

Department of Radiology, University of Michigan, Ann Arbor, MI 48109, USA., Department of Internal Medicine-Hematology/Oncology, University of Michigan, Ann Arbor, MI 48109, USA., Department of Internal Medicine-Hematology/Oncology, University of Iowa, Iowa, IA 52242, USA., Department of Internal Medicine-Hematology/Oncology, Pennsylvania State University, Hershey, PA 16801, USA., Department of Neurology, University of Michigan, Ann Arbor, MI 48109, USA., U.S. Food and Drug Administration, Center for Devices and Radiological Health, Silver Spring, MD 20993, USA., Department of Radiology, Acibadem City Clinic, Tokuda Hospital, 1407 Sofia, Bulgaria., Department of Urology, University of Michigan, Ann Arbor, MI 48109, USA., Department of Radiation Oncology, University of Michigan, Ann Arbor, MI 48109, USA.

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