Heated Intravesical Chemotherapy: Biology and Clinical Utility.

Non-muscle-invasive bladder cancer can be a challenging disease to manage. In recent years, hyperthermia therapy in conjunction with intravesical therapy has been gaining traction as a treatment option for bladder cancer, especially if Bacillus Calmette-Guerin might not be available.

Trials of intravesical chemotherapy with heat are few and there has been considerable heterogeneity between studies. However, multiple new trials have accrued and high-quality data are forthcoming. In this review, we discuss the role of combined intravesical hyperthermia and chemotherapy as a novel approach for the treatment of bladder cancer.

The Urologic clinics of North America. 2020 Feb [Epub]

Wei Phin Tan, Thomas A Longo, Brant A Inman

Division of Urology, Duke University Medical Center, Durham, NC 27710, USA., Division of Urology, Duke University Medical Center, Durham, NC 27710, USA. Electronic address: .

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