The study identified 214/570 patients who had disease recurrence. The majority of recurrences occurred early with a median 13.0 (interquartile range [IQR], 6.0–32.0) months to recurrence. 20 (9.3%) patients had a late recurrence. Median time from RC to recurrence was 85.0 (IQR 72.5–124.5) months for the late recurrence group. There were no statistically significant differences in post-recurrence disease-specific survival at five years between the late recurrence (21.6%) and the early recurrence groups (14.1%) (p = 0.344).
Older age (Hazard Ratio HR 1.03, 95% CI 1.01–1.05, p = 0.001), nonorgan-confined disease at RC (HR 1.73, 95% CI 1.15–2.61, p = 0.008), and lymph node invasion (HR 1.58, 95% CI 1.01–2.45, p = 0.043) predicted post-recurrence 5-year disease-specific survival.
Written by: Bishoy M. Faltas, MD, Director of Bladder Cancer Research, Englander Institute for Precision Medicine, Weill Cornell Medicine
Reference:
1. Yoo SH, Kim H, Kwak C, Kim HH, Jung JH, Ku JH. Late Recurrence of Bladder Cancer following Radical Cystectomy: Characteristics and Outcomes. Urol Int. 2019 Aug 28:1-6. doi: 10.1159/000502656.
Read the Abstract
Written by: Bishoy M. Faltas, MD, Director of Bladder Cancer Research, Englander Institute for Precision Medicine, Weill Cornell Medicine
Reference:
1. Yoo SH, Kim H, Kwak C, Kim HH, Jung JH, Ku JH. Late Recurrence of Bladder Cancer following Radical Cystectomy: Characteristics and Outcomes. Urol Int. 2019 Aug 28:1-6. doi: 10.1159/000502656.
Read the Abstract