Detailed Analysis of Urinary Tract Infections after Robot-Assisted Radical Cystectomy.

To describe urinary tract infections (UTIs) after robot-assisted radical cystectomy (RARC) and investigate the variables associated with it.

A retrospective review of 616 patients who underwent RARC 2005-2019 was performed.

Patients were divided into those who developed UTI and those who did not. Patients who developed UTI were further subdivided into three subgroups according to the onset, number and severity. Kaplan-Meier method was used to depict time to UTI. Multivariate analysis was used to investigate variables associated with UTI.

240 (39%) patients were diagnosed with UTI after RARC; 48% occurred within 30-days, 17% within 30-90 days, and 35% at 90 days after RARC. 23% of the patients presented with urosepsis. The median (IQR) time to develop UTI was 1 (0.3, 7) month. On multivariate analysis, patients who received neobladders (OR 2.80; 95% CI 1.50-5.20; p < 0.01), prolonged hospital stay (OR 1.06; 95% CI 1.03-1.08; p < 0.01), receiving adjuvant chemotherapy (OR 2.20; 95% CI 1.40-3.60; p < 0.01), had poor renal function postoperatively (OR 2.30; 95% CI 1.30-3.80; p<0.01), postoperative hydronephrosis (OR 2.50; 95% CI 1.40-4.50; p < 0.01), ureteroileal anastomotic stricture (OR 2.90; 95% CI 1.50-5.70; p < 0.01) and stented ureteroileal anastomosis (OR 9.35; 95% CI 1.23-71.19; p = 0.03) were associated with UTI after RARC.

UTI is common after RARC mainly within 1st month after RARC. Enterococcus Fecalis was the most common causative organism.

Journal of endourology. 2020 Jul 14 [Epub ahead of print]

Naif A Aldhaam, Ahmed Hussein, Ahmed S Elsayed, Zhe Jing, Jennifer Osei, Zachary Kurbiel, Tarik Babar, Sara Khan, Avneet Nagra, Brahm Segal, Qiang Li, Khurshid A Guru

Roswell Park Cancer Institute, 2074, Urologic Oncology , Buffalo, New York, United States; ., 11 Linwood aveBuffalo, United States, 14209; ., Roswell Park Cancer Insitute, Urologic Oncology, Buffalo, New York, United States., Roswell Park Cancer Insitute, Urologic Oncology, Buffalo, New York, United States; ., Roswell Park Cancer Insitute, Urologic Oncology, Buffalo, New York, United States; ., Roswell Park Cancer Insitute, Urologic Oncology, Buffalo, New York, United States; ., Roswell Park Cancer Insitute, Urologic Oncology, Buffalo, New York, United States; ., Roswell Park Cancer Insitute, Urologic Oncology, Buffalo, New York, United States; ., Roswell Park Cancer Insitute, Urologic Oncology, Buffalo, New York, United States; ., Roswell Park Cancer Insitute, Urologic Oncology, Buffalo, New York, United States; ., Roswell Park Cancer Insitute, Urologic Oncology, Buffalo, New York, United States; ., Roswell Park Cancer Insitute, Urologic Oncology, Elm and Carlton Streets, Buffalo, New York, United States, 14263.

Go Beyond the Abstract and Read a Commentary by the Author

email news signup