Review of underactive bladder

In clinical practice, many patients cannot empty their bladders within an acceptable duration. Common complaints include weak urinary stream and incomplete emptying, which may affect quality of life. Bladder emptying requires sufficient detrusor contractile power, velocity, and durability. The urodynamic term for inadequate detrusor contraction is detrusor underactivity (DU). Although this definition was provided by the ICS, it may not be clinically practical. Analogous to the relationship between overactive bladder (OAB) and detrusor overactivity (DO), the symptom complex caused by DU is termed underactive bladder (UAB). Many conditions lead to UAB, such as advanced age, neurogenic bladder and BOO, but the definite pathophysiology directly leading to UAB is still being widely studied without a widely-accepted consensus. The preferred mainstream treatment for increased residual urine volume caused by UAB is intermittent catheterization, while pharmacotherapy is still disappointing after decades of development. There are no studies on surgical treatment for UAB with an acceptable level of evidence. We reviewed the recent literature on UAB and DU to provide a comprehensive discussion of the related presentation, etiology, diagnosis and management.

Journal of the Formosan Medical Association = Taiwan yi zhi. 2017 Sep 29 [Epub ahead of print]

Yi-Huei Chang, Justin Ji-Yuen Siu, Po-Jen Hsiao, Chao-Hsiang Chang, Eric Chieh-Lung Chou

Department of Urology, China Medical University Hospital, Taichung 40447, Taiwan., Department of Urology, China Medical University Hospital, Taichung 40447, Taiwan; School of Medicine, College of Chinese Medicine, China Medical University, Taichung 40402, Taiwan., Department of Urology, China Medical University Hospital, Taichung 40447, Taiwan; School of Medicine, College of Chinese Medicine, China Medical University, Taichung 40402, Taiwan. Electronic address: .

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