Is pre-operative urodynamic bladder function the true predictor of outcome of male sling for post prostatectomy incontinence?

To investigate pre-operative urodynamic parameters in male sling patients to ascertain whether this might better predict surgical outcomes and facilitate patient selection.

We performed a retrospective, case notes and video-urodynamics, review of men who underwent AdVanceXP male sling in three London hospitals between 2012 and 2019. Urodynamics were performed in all centres, while retrograde leak point pressure (RLPP) was performed in one centre.

Successful outcome was seen in 99/130 (76%) of men who required one pad or less per day. The dry rate was 51%. Pad usage was linked to worse surgical outcomes, mean 2.6 (range 1-6.5) for success vs 3.6 (range 1-10) although the ranges were wide (p = 0.002). 24 h pad weight also reached statistical significance (p = 0.05), with a mean of 181 g for success group versus 475 g for the non-successful group. The incidence of DO in the non-successful group was significantly higher than in successful group (55% versus 29%, p = 0.0009). Bladder capacity less than 250 ml was also associated with worse outcomes (p = 0.003). Reduced compliance was not correlated with outcomes (31% for success groups vs 45% for non-successful group, p = 0.15). Preoperative RLPP was performed in 60/130 patients but did not independently reach statistical significance (p = 0.25).

Urodynamic parameters related to bladder function-detrusor overactivity and reduced maximum cystometric capacity predict male sling outcomes and may help in patient selection for male sling (or sphincter) surgery; whereas urodynamic parameters of sphincter incompetency (RLPP) were not predictive. Further larger scale studies are required to confirm these findings.

World journal of urology. 2020 Jun 06 [Epub ahead of print]

Bogdan Toia, Lap Yan Leung, Raveen Saigal, Eskinder Solomon, Sachin Malde, Claire Taylor, Arun Sahai, Rizwan Hamid, Jai H Seth, Davendra Sharma, Tamsin J Greenwell, Jeremy L Ockrim

University College London, Gower St, Bloomsbury, London, WC1E 6BT, UK. ., St George's University Hospital, Blackshaw Rd., Tooting, London, SW17 0QT, UK., Guy's and St Thomas' NHS Foundation Trust, King's College London, London, SE1 9RT, UK., Department of Urology, University College London Hospital, 16-18 Westmoreland Street, London, W1G 8PH, UK., University College London, Gower St, Bloomsbury, London, WC1E 6BT, UK.