Treatment with transcutaneous posterior tibial neurostimulation (NTPT) has been shown to be effective in the treatment of overactive bladder (OAB), but its outcomes in diabetic patients have never been assessed. The aim of this study was to compare the efficacy of NTPT in diabetic OAB patients and in OAB patients without diabetes.
A single-center prospective study included all patients treated with NTPT for lower urinary tract storage symptoms between 2012 and 2016. The primary endpoint was symptoms improvement≥50% assessed using a Visual Analog Scale (VAS) two months after starting NTPT. Treatment consisted in a daily 20-minute NTPT single-session. The secondary endpoints were lower urinary tract symptoms reported by bladder diary, the Urinary Symptom Profile, the impact on mood and on daily activities.
Seventy-one patients were included, 10 of whom were diabetic. The efficacy rate (EVA>50%) was not significantly different in the diabetic group (70% vs. 44.1%, P=0.17), like the mean EVA efficacy was similar in both groups (4/10 vs. 4/10, P=0.98). OAB USP sub-score diminished significantly in both groups at 2 months (-3 points in the diabetic group; -1.9 points in the non-diabetic group; P=0.03 and P<0.0001, respectively). There was no significant difference between the groups, except for the rate of patients who stopped treatment at 6 months, higher in diabetic patients (100% vs. 63.5%, P=0.04).
The functional outcomes of NTPT appear to be similar in the treatment of OAB in diabetic patients and in non-diabetic patients.
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Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie. 2017 Sep 27 [Epub ahead of print]
L Mathieu, B Peyronnet, N Senal, S Fontaine, A Manunta, T Honoré, J Hascoet, M Damphousse, I Bonan, J Kerdraon
Service de médecine physique et rééducation, CHU de Rennes, 35000 Rennes, France; Université Rennes 1, 35000 Rennes, France. Electronic address: ., Université Rennes 1, 35000 Rennes, France; Service d'urologie, CHU de Rennes, 35000 Rennes, France; Équipe thématique INPHY CIC 1414, Inserm UMR 991, CHU de Rennes, 35000 Rennes, France., Service de médecine physique et rééducation, CHU de Rennes, 35000 Rennes, France; Université Rennes 1, 35000 Rennes, France., Service de médecine physique et rééducation, CHU de Rennes, 35000 Rennes, France., Service d'urologie, CHU de Rennes, 35000 Rennes, France., Université Rennes 1, 35000 Rennes, France; Service d'urologie, CHU de Rennes, 35000 Rennes, France., Service de médecine physique et rééducation, CHU de Rennes, 35000 Rennes, France; Centre de rééducation de Kerpape, 56270 Ploemeur, France.