Prevalence of Spina Bifida Occulta and Its Relationship With Overactive Bladder in Middle-Aged and Elderly Chinese People

To investigate the prevalence of spina bifida occulta (SBO) and its relationship with the presence of overactive bladder (OAB) in middle-aged and elderly people in China.

A cross-sectional community-based survey was carried out at 7 communities in Zhengzhou City, China from December 15, 2013 to June 10, 2014, where residents aged over 40 years were randomly selected to participate. All of the participants underwent lumbosacral radiographic analysis and relevant laboratory tests. A questionnaire including basic information, past medical history and present illness, and the OAB symptom score was filled out by all participants. Chi-square tests and logistic regression were used for data analysis with a P-value of <0.05 denoting statistical significance.

A total of 1,061 subjects were qualified for the final statistical analysis (58.8±11.7 years; male, 471 [44.4%]; female, 590 [55.6%]). The overall prevalence of SBO was 15.1% (160 of 1,061): 18.3% (86 of 471) in men and 12.5% (74 of 590) in women. Among these subjects, 13.7% (145 of 1,061) had OAB: 13.2% (62 of 471) in men and 14.1% (83 of 590) in women. The results of logistic regression showed that age, SBO, history of cerebral infarction (HCI), and constipation were risk factors for OAB (P<0.05), while sex, history of childhood enuresis (HCE), body mass index (BMI), and diabetes mellitus (DM) were not (P>0.05). In men, age, SBO, and constipation were risk factors for OAB (P<0.05), while HCE, BMI, DM, HCI, and benign prostate hyperplasia were not (P>0.05). In women, age, SBO, and HCI were risk factors for OAB (P<0.05), while HCE, BMI, DM, vaginal delivery, and constipation were not (P>0.05).

The prevalence of SBO is high and it is related to OAB in middle-aged and elderly people in China.

International neurourology journal. 2016 Jun 24 [Epub]

Jun Wei Wu, Yu Rong Xing, Yi Bo Wen, Tian Fang Li, Jia Feng Xie, Quan De Feng, Xiao Ping Shang, Yun Long Li, Jin Jin Feng, Xin Xin Wang, Rong Qun Zhai, Xiang Fei He, Tao Chen, Xin Jian Liu, Jian Guo Wen

Urodynamic Centre, Department of Urology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China., Center of Health Examination, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China., Urodynamic Centre, Department of Urology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China., Department of Rheumatology & Immunology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China., Urodynamic Centre, Department of Urology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China., Urodynamic Centre, Department of Urology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China., Medical Record Department, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China., Urodynamic Centre, Department of Urology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China., Urodynamic Centre, Department of Urology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China., Reproductive Medical Centre, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China., Urodynamic Centre, Department of Urology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China., Urodynamic Centre, Department of Urology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China., Urodynamic Centre, Department of Urology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China., Urodynamic Centre, Department of Urology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China., Urodynamic Centre, Department of Urology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.