Detrusor under-activity (DU) is an increasingly recognised cause of lower urinary tract symptoms in both men and women.
There has been a lack of research into all aspects of this dysfunction, and as yet, no effective treatments exist. DU can be diagnosed at present only on the basis of an invasive urodynamic study. An international consensus group met at the International Consultation on Incontinence-Research Society and International Continence Society annual meetings in 2014 to consider the feasibility of developing a working definition of a symptom complex associated with DU. Drawing an analogy to detrusor overactivity (urodynamic diagnosis) and overactive bladder (symptom complex), the aim of this process is to help identify affected patients and facilitate further clinical and epidemiological research.
PATIENT SUMMARY: Bladder under-activity is an under-researched but important cause of urinary symptoms in men and women. In this paper, an international expert group presents a working definition for the symptoms that characterise bladder under-activity, with the aim of facilitating further research in this area.
Written by:
Chapple CR, Osman NI, Birder L, van Koeveringe GA, Oelke M, Nitti VW, Drake MJ, Yamaguchi O, Abrams P, Smith PP. Are you the author?
Department of Urology, Royal Hallamshire Hospital, Sheffield, UK; Department of Medicine, University of Pittsburgh, Pittsburgh, PA, USA; Department of Urology, Maastricht University Medical Centre, The Netherlands; Department of Urology, Hannover Medical School, Hannover, Germany; Department of Urology, New York University Medical Center, New York, NY, USA; Bristol Urological Institute, Southmead Hospital, Bristol, UK; Division of Bioengineering and LUTD Research, Nihon University School of Engineering, Koriyama, Japan; Department of Surgery and Center on Aging, University of Connecticut Health Center, Farmington, CT, USA.
Reference: Eur Urol. 2015 Mar 11. pii: S0302-2838(15)00195-5.
doi: 10.1016/j.eururo.2015.02.030
PubMed Abstract
PMID: 25770481