Deep endometriosis and bladder and detrusor functions in women without urinary symptoms: A pilot study through an unexplored world - Abstract

OBJECTIVE: To evaluate the impact of deep endometriosis (DE) on bladder function, focusing on detrusor pattern, in patients without preoperative urinary symptoms.

DESIGN: Prospective study.

SETTING: Academic research center.

PATIENT(S): A total of 25 asymptomatic patients: 12 patients with DE (group 1) and 13 patients with ovarian endometriosis (group 2, control group).

INTERVENTION(S): Preoperative urodynamic evaluation.

MAIN OUTCOME MEASURE(S): The impact of DE on urodynamic parameters.

RESULT(S): For the first time, a urodynamic diagnosis of detrusor overactivity was correlated with the presence of deep infiltrating endometriosis (group 1, 91.7% [11/12] vs. group 2, 7.7% [1/13]). All involuntary detrusor contractions were detected only during the filling phase. All cystometry parameters were found to be altered in group 1 and statistically different between the two groups. No pressure/flow study parameter significantly differed between the two groups, besides maximal detrusor pressure (46 cmH2O [33-79] vs. 29 cmH2O [15-40]), which was significantly higher in group 1. Therefore, all detrusor-related parameters are statistically different between the two groups. Postvoid residual does not reach a statistically significant difference.

CONCLUSION(S): DE could significantly impair detrusor functions. A preoperative urodynamic evaluation allows the attainment of important functional information, even in asymptomatic patients.

Written by:
Serati M, Cattoni E, Braga A, Uccella S, Cromi A, Ghezzi F.   Are you the author?
Department of Obstetrics and Gynecology, University of Insubria, Varese, Italy.

Reference: Fertil Steril. 2013 Jul 24. pii: S0015-0282(13)00744-9.
doi: 10.1016/j.fertnstert.2013.06.044


PubMed Abstract
PMID: 23891020

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