PURPOSE: In analysis of a bladder diary with the patient's self-reported urinary perception grades, we developed a quantitative measure of bladder hypersensitivity, which we refer to as the urge perception index (UPI).
The aim of this study was to evaluate the impact of the UPI on defining the severity of overactive bladder (OAB).
MATERIALS AND METHODS: We retrospectively evaluated 69 female patients to visit our outpatient clinic with complaining storage symptoms. The patients were asked to complete OAB symptom score, and a 3-day bladder diary with a self-reported grading of urinary perception (range 1 to 5) per void, and diagnosed as OAB (n=43) or non-OAB (n=26). UPI was defined as a quotient of voided volume/urinary perception grade at every single void.
RESULTS: A total of 1578 voids reporting were analysed. According to the grade of urinary perception, values of UPI in OAB demonstrated significantly lower values than those in non-OAB (p< 0.001 in all perception grades of 1-4). The averages of UPIs in 3-day bladder diary was lower in OAB (55±28) than non-OAB (133±73) (p< 0.0001). The most severe (the lowest) single UPI value during the 3-day was significantly lower in OAB (20±12) than non-OAB (62±40) (p< 0.0001). There were negative linear correlations of UPI value with total OAB symptom scores (r=-0.598, p< 0.0001) and with a symptom score of urgency (r=-0.557, p< 0.0001).
CONCLUSIONS: UPI, the integrated parameter of patient-reported bladder perception and voided volume, could be promising for quantifying the severity of OAB or bladder hypersensitivity through the analysis of a bladder diary.
Fujihara A, Ukimura O, Honjo H, Iwata T, Ueda T, Matsugasumi T, Kamoi K, Okihara K, Kawauchi A, Miki T. Are you the author?
Department of Urology, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Reference: J Urol. 2012 Nov 28. pii: S0022-5347(12)05626-1.