Neuromodulation as a treatment for overactive bladder syndrome - Abstract

Neuromodulation is used as a treatment for overactive bladder syndrome, if conservative management is ineffective or only partially effective.

Sacral neuromodulation is now a minimally invasive treatment as a result of improvements in surgical technique, and it has good long-term results. Nevertheless the risk of complications such as pain and decreasing effect is still present. Developments in alternative neuromodulation treatments, such as posterior tibial nerve stimulation, pudendal nerve stimulation and intravesical injection therapy with botulinum neurotoxin, have extended the role of neuromodulation. Intravesical injection therapy with botulinum toxin, along with sacral neuromodulation, has been included in the treatment algorithm of overactive bladder syndrome if this does not respond to conservative therapy. When choosing for a neuromodulation therapy, the side-effects and complications of the treatments should be considered alongside the specific patient situation and evidence for effectiveness and long-term effectiveness.

Written by:
Smits MA, Marcelissen TA, van Kerrebroeck PE, de Wachter SG.   Are you the author?
Maastricht Universitair Medisch Centrum, afd. Urologie, Maastricht.

Reference: Ned Tijdschr Geneeskd. 2012;156(33):A4135.

PubMed Abstract
PMID: 22894803

Article in Dutch. Overactive Bladder (OAB) Section