Department of Surgery, Division of Urology, University of Pennsylvania School of Medicine, Perelman Center for Advanced Medicine, 3 West, Philadelphia, PA, 19104, USA.
When incontinence accompanies detrusor overactivity (DO), the pressure at which it occurs may have important predictive value and should be termed DO leak point pressure (DOLPP).
A retrospective review of our video urodynamics database (n = 222) including validated questionnaires was performed. DOLPP was defined as detrusor pressure the moment DO incontinence occurred. Statistical analysis was performed using Student's t-test.
Women with DO leakage (47) and with DO without leakage (15) were analyzed. Urgency and urgency incontinence (UUI) were greater among patients with DO leakage. A link between sphincter deficiency and greater severity of UUI was noted. Among patients with DO leakage, those with subjective mixed incontinence had a lower mean DOLPP than those with pure UUI (p = 0.004). The detrusor pressure at peak flow was lower in the DO leakage group (versus DO alone, p = 0.05) likely reflecting a measure of outlet resistance.
DOLPP has predictive meaning in women and should be further studied for possible inclusion in standard urodynamic terminology.
Written by:
Smith AL, Jaffe WI, Wang M, Wein AJ. Are you the author?
Reference: Int Urogynecol J. 2011 Oct 19. Epub ahead of print.
doi: 10.1007/s00192-011-1587-9
PubMed Abstract
PMID: 22008739
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