Psychological and psychiatric factors as predictors for success in sacral neuromodulation treatment - Abstract

Departments of Urology and Clinical Epidemiology and Medical Technology Assessment, Maastricht University Medical Centre, Maastricht, the Netherlands.

School of Psychology, Open University of the Netherlands, Heerlen, the Netherlands.



Study Type - Therapy (preference) Level of Evidence 4.

What's known on the subject? and What does the study add? Sacral neuromodulation (SNM) is a well-established treatment for patients with chronic LUTS. The selection of eligible candidates could be improved by identifying factors that can predict a successful response. In the present study, we evaluated the role of various psychological and psychiatric factors in relation to SNM treatment.

To evaluate if psychological and psychiatric factors can predict the outcome of test stimulation or permanent treatment with sacral neuromodulation (SNM).

Between 2006 and 2009, patients with overactive bladder syndrome or non-obstructive urinary retention who were eligible for test stimulation were included. All patients completed the Amsterdam Biographic Questionnaire (ABQ), which measures the personality traits of the patient, and the Symptom Check-List-90-Revised (SCL-90-R), which is a screening instrument for neuroticism, and for current level of complaints. The results of the questionnaires were compared with the outcomes of test stimulation and permanent treatment. In addition to the questionnaires, we also included the psychiatric history as a potential predictive factor.

On univariate analysis there was no relationship between the psychological characteristics and the outcome of test stimulation or the occurrence of adverse events (AEs) with permanent treatment. A history of psychiatric disease was not related to the outcome of test stimulation, but was shown to be a positive predictor for the occurrence of AEs with permanent SNM treatment.

In the present study there was no evidence that psychological screening with the ABQ or SCL-90-R can predict the outcome of SNM treatment. Patients with a medical history of psychiatric disease appear to be more likely to encounter AEs with permanent SNM treatment.

Written by:
Marcelissen TA, Leong RK, Nieman FH, van Lankveld JJ, van Kerrebroeck PE, de Wachter SG.   Are you the author?

Reference: BJU Int. 2011 Aug 2. Epub ahead of print.
doi: 10.1111/j.1464-410X.2011.10205.x

PubMed Abstract
PMID: 21810157 Overactive Bladder (OAB) Section



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