Impact of overactive bladder on retrograde ejaculation

To evaluate the impact of overactive bladder disorder on patients diagnosed with retrograde ejaculation.

Retrospective analysis of prospective collected database made. Questionnaires conducted in urology polyclinics in five different centers.

International Index of Erectile Function - 5 (IIEF - 5), Overactive Bladder 8 - Question Awareness Tool (OAB - V8), urodynamics, semen analysis. The participants of the study were n = 120 patients. There was retrograde ejaculation (RE) in only n = 47 patients (non / minimal symptomatic patients), n = 73 patients had RE and overactive (OAB) complaints (symptomatic patients) and received anticholinergic treatment (trospium), n = 37 control group patients who only had OAB and received an anticholinergic.

While no difference was observed in overactive bladder examination and urodynamic values between the non / minimal symptomatic group and the symptomatic group (p > 0.05), sperm was detected and identified as fructose positive in post - ejaculation urine in the symptomatic group. Thus, it was possible to demonstrate the differences between symptomatic patients and non - symptomatic patients. Consequently, following three - month daily treatment with trospium 30 mg 2 x 1 in the control group and the symptomatic group, it was observed that an evident increase was observed in the sperm count and ejaculate volume in the symptomatic group and that no change was observed in the control group (p < 0.05).

This clinical study is the first of its kind in terms of revealing the coexistence of RE with OAB upon performing urodynamics and showing that treatment is possible in selected patients.

International braz j urol : official journal of the Brazilian Society of Urology. 2018 Aug 10 [Epub ahead of print]

Ahmet Salvarci, Mehmet Karabakan, Aliseydi Bozkurt, Erkan Hirik, Binhan Kagan Aktaş

Department of Urology, Novafertile IVF Centers and Konya Hospital, Konya, Turkey., Department of Urology, Mersin Toros State Hospital, Mersin, Turkey., Department of Urology, Erzincan University, Mengücek Gazi Research and Training Hospital, Erzincan, Turkey., Department of Urology, Ankara Numune Research and Training Hospital, Ankara, Turkey.