Evaluation of Sexual Dysfunction, Lower Urinary Tract Symptoms and Quality of Life in Men with Obstructive Sleep Apnea Syndrome and The Efficacy of Continuous Positive Airway Pressure Therapy

To determine the presence of lower urinary tract symptoms (LUTS), nocturia, sexual dysfunction (SD) and the status of quality of life (QOL) in men with obstructive sleep apnea syndrome (OSAS) and after continuous positive airway pressure (CPAP) treatment, the changes in the presence of these conditions and the improvements of QOL.

In this study, 126 patients with suspicious diagnosis of OSAS were enrolled prospectively. International Prostate Symptom Score (IPSS), International Consultation on Incontinence Questionnaire-Male LUTS (ICIQ-MLUTS), Overactive Bladder Symptoms Score (OABS-V8), Nocturia Quality of Life (Nqol), voiding diary, International Index of Erectile Function (IIEF-15) questionnaire and Short form 36 (SF-36) to assess the presence of SD, LUTS, nocturia and the status of QOL were filled by patients before polysomnography. The same forms were filled in the third month of treatment by the patients directed to CPAP treatment due to moderate and severe OSAS.

There were significant differences in IPSS, IIEF, OABSS, ICIQ-MLUTS, Nqol and SF-36 scores, frequency of nocturia and night-time urine volume according to OSAS severity. Among the factors affecting the quality of life, there was strong correlation between ED and SF-36 sub-domains compared to the other factors. After CPAP treatment significant changes and improvements on these symptoms and QOL were observed.

In patient with OSAS, the severity of SD and LUTS and their effect on QOL differ according to the severity of OSAS and CPAP treatment improves the negative impact of these conditions on QOL.

Urology. 2018 Aug 14 [Epub ahead of print]

Bora İrer, Aylin Çelikhisar, Hakan Çelikhisar, Ozan Bozkurt, Ömer Demir

Department of Urology, Izmir Metropolitan Municipality Eşrefpaşa Hospital, Izmir, Turkey. Electronic address: ., Department of Chest Disease, Izmir Metropolitan Municipality Eşrefpaşa Hospital, Izmir Turkey., Department of Urology, Dokuz Eylül University School of Medicine, Izmir, Turkey.