Feasibility of water vapor thermal therapy for treating lower urinary tract symptoms in men with localized prostate cancer on active surveillance: a case series.

Prostate cancer is a common malignancy, with many men on active surveillance for localized, low-risk disease also experiencing lower urinary tract symptoms (LUTS) from benign prostatic hyperplasia (BPH). Water Vapor Thermal Therapy (WVTT) is a minimally invasive BPH treatment, but its safety and efficacy in this setting are unclear.

We report three men with localized PCa on active surveillance who underwent WVTT for LUTS.

WVTT appears safe and potentially effective in treating LUTS, especially in those with lower-risk disease and smaller prostate volumes. Further research is needed to confirm safety, efficacy, and optimal patient selection.

The Canadian journal of urology. 2026 Feb 28*** epublish ***

Mustufa Babar, Farooz Babar, Noah Hawks-Ladds, Justin Loloi, Michael Ciatto

Hackensack Meridian Health, Palisades Medical Center, North Bergen, NJ 07047, USA., St. George's University School of Medicine, University Centre, Grenada, P.O. Box 7, West Indies., Albert Einstein College of Medicine, Bronx, NY 10461, USA., Department of Urology, Montefiore Medical Center, Bronx, NY 10467, USA., DSS Urology, Queens Village, NY 11427, USA.