Bladder pain syndrome/interstitial cystitis is associated with asthma: A case-control study

Although asthma and bladder pain syndrome/interstitial cystitis (BPS/IC) are considered to share similar pathophysiological pathways, the relationship between asthma and BPS/IC is uncertain. This case-control study aimed to investigate the relationship between prior asthma and BPS/IC using a large database in Taiwan.

This study used data from the Taiwan Longitudinal Health Insurance Database 2005. We identified 500 female patients with BPS/IC as cases and 500 propensity score-matched females without BPS/IC as controls. We conducted logistic regressions to estimate the odds ratio (OR) and 95% confidence interval (CI) for prior asthma between cases and controls.

Results indicated that 143 (14.30%) of the total sampled patients had received a prior diagnosis of asthma. Moreover, prior asthma was found in 86 (17.20%) cases and 57 (11.40%) controls. The OR of prior asthma for cases was 1.61 (95%CI: 1.13-2.32) compared to propensity score-matched controls. Additionally, the ORs of prior asthma for females with BPS/IC aged 18-59 and ≥60 years were 1.72 (95%CI: 1.11-2.69) and 1.40 (95%CI: 0.74-2.62), respectively, compared to controls.

We concluded that prior asthma was significantly associated with BPS/IC in a female Taiwanese population.

Neurourology and urodynamics. 2018 Feb 14 [Epub ahead of print]

Shiu-Dong Chung, Chung-Chien Huang, Herng-Ching Lin, Li-Ting Kao

Division of Urology, Department of Surgery, Far Eastern Memorial Hospital, Banciao, New Taipei City, Taiwan., School of Health Care Administration, Taipei Medical University, Taipei, Taiwan., Sleep Research Center, Taipei Medical University Hospital, Taipei, Taiwan.