Does Kidney Transplantation Help Young Patients on Dialysis with Erectile Dysfunction? A Single-Center Study.

to investigate the effects of a successful KT on EF in male patients with ESRD .

A single-center cross-sectional prospective study to assess the erectile dysfunction in male patients one month before and one year after KT. We adopted a validated, self-administered translated International Index of Erectile Function (IIEF-15) questionnaire. A sub-analysis was performed by categorizing the cohort into two age groups: <50 and ≥50 yr .

Between September 2017 and February 2021, 68 ESRD patients underwent kidney transplantation (KT), with a mean age of 48.9 ± 12.9 years. Thirty-one patients were below 50 years (Group I). The median hemodialysis duration was 12 months. Sixty-three patients (92.6%) had ED. The mean total IIEF-15 score before and after was 46.8/75 ±12.7 and 55.5 ±13, respectively (P < .001). Forty-six patients (67.6%) reported improved erectile function, 22 (32.4%) did not demonstrate any change, and no patient reported deterioration. Moreover, after KT, sexual desire, orgasm, and overall patient satisfaction improved significantly. Before KT, 83.8% and 100% of groups I and II patients had ED, which dropped to 22.6% and 86.5%, respectively, after KT. IIEF-15 scores improved in both groups. However, the improvement in ED was observed significantly in young patients with mild ED .

KT positively impacts sexual function and improves erectile dysfunction, especially among young patients. The duration of dialysis before kidney transplantation had no impact on ED improvement after transplantation. The positive effect of transplantation on ED could encourage ESRD patients to undergo KT.

Urology. 2022 Aug 06 [Epub ahead of print]

Hany M El Hennawy, Omar Safar, Abdullah S Al Faifi, Osama Shalkamy, Yahia Alqahatani, Weam El Nazer, Ahmed Mahedy, Mohammed Abdelrahim Ali, Eisa Al Atta, Abdelaziz A Abdelaziz, Ahmed Al Malki, Naveed Mirza, Ali Al Fageeh, Mohammad F Zaitoun, Adel Elatreisy

Surgery Department, Section of Transplantation, Armed Forces Hospitals Southern Region, Khamis Mushayte, 101, KSA. Electronic address: ., Urology Department, Armed Forces Hospitals Southern Region, Khamis Mushayte, 101, KSA., Surgery Department, Section of Transplantation, Armed Forces Hospitals Southern Region, Khamis Mushayte, 101, KSA., Urology Department, Armed Forces Hospitals Southern Region, Khamis Mushayte, 101, KSA; Urology Department, Faculty of Medicine, Al Azhar University, Cairo, Egypt., Nephrology Department, Armed Forces Hospitals Southern Region, Khamis Mushayte, 101, KSA., Pharmacy Department, Armed Forces Hospitals Southern Region, Khamis Mushayte, 101, KSA.

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