To analyze the blood biochemical characteristics of the ED patients with different types of kidney deficiency or non-kidney deficiency.
We reviewed the clinical data on 156 ED patients treated in our Department of Andrology from May to July 2018 and, according to the traditional Chinese medicine (TCM) syndromes, divided them into four groups: kidney-yang deficiency (n = 48), kidney-yin deficiency (n = 34), kidney-yin+yang deficiency (n = 36) and non-kidney deficiency control (n = 38). We obtained and compared their blood biochemical indexes, including the levels of testosterone (T), estradiol (E2), cortisol (CORT), thyroid stimulating hormone (TSH), free thyroxine (FT4), free triiodothyronine (FT3), nitric oxide (NO), total nitric oxide synthase (tNOS), and inducible nitric oxide synthase (iNOS).
There were no statistically significant differences in the mean age, course of disease, IIEF-5 score and erection hardness score (EHS) among the four groups of patients. Pairwise comparison showed that, compared with the non-kidney deficiency controls, the patients in the kidney-yin deficiency group exhibited a dramatically higher level of CORT (［87.97 ± 45.59］ vs ［121.78 ± 41.87］ μg/L, P = 0.002) and those in the kidney-yang deficiency group a remarkably lower level of FT3 (［5.44 ± 0.38］ vs ［5.11 ± 0.54］ pmol/L, P = 0.008). The iNOS level was significantly higher in the kidney-yin deficiency group (14.42 ± 2.49 U/ml) than in either the control (12.71 ± 2.58 U/ml) (P = 0.039) or the kidney-yang deficiency group (13.05 ± 2.17 U/ml) (P =0.049).
ED patients with different types of kidney deficiency syndromes have different blood biochemical indexes, which may help clarify the biological basis of the TCM syndromes of kidney deficiency in ED patients.
Zhonghua nan ke xue = National journal of andrology. 2020 Jul [Epub]
Rui Wang, Tian-Biao Zhang, Kun-Long Lü, Tao Zheng, Zheng-Wei Yin, Ya-Wei Hao, Yong-Hao Nan, Wei-Xing Zhang
Department of Andrology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450000, China.