The relationships between metabolic syndrome, erectile dysfunction and lower urinary tract symptoms associated with benign prostatic hyperplasia

To determine the relationship between erectile dysfunction and metabolic syndrome (MetS) in patients with benign prostatic hyperplasia (BPH) and lower urinary tract symptoms (LUTS).

Seventy-eight patients who were admitted to our outpatient clinic because of BPH-related LUTS over 40 years of age were included in the study.

Patients with LUTS and erectile dysfunction (ED) were evaluated by International Prostate Symptom Score (IPSS) and International Index of Erectile Function-5 (IIEF-5) forms. The National Cholesterol Education Program Adult Treatment Panel III criteria was used for the diagnosis of MetS. LUTS were classified as mild, moderate, and severe according to IPSS and ED was classified as mild- moderate, moderate, and severe according to the IIEF-5. For the evaluation of data, descriptive statistical methods (mean, standard deviation, median, frequency, ratio, minimum, and maximum) and also for the comparison of the variables with non-normal distribution in 3 or more than 3 groups Student's t test, Mann-Whitney U, ANOVA, chi-square, Fisher Exact tests, and Pearson correlation analysis were used. P

Mean age of the patients included in the study was 61. 83±9. 15. In 34. 6% of the patients with MetS, 70. 5% of the patients with ED and 37. 2% of the patients with severe LUTS were determined. There were no significant differences between the mean age of patients with and without metabolic syndrome (p>0. 05). There was a positive correlation with age and severity of LUTS but this relationship was not found to be statistically significant (p>0. 05). Mean age of the patients with ED was significantly higher than those without (p

In patients with LUTS as a consequence of BPH, when severity of symptoms increases, frequency of MetS increases proportionally and severe ED is observed much more frequently.

Turkish journal of urology. 2015 Mar [Epub]

Yunus Doğan, Fatih Uruç, Bekir Aras, Aytaç Şahin, Mithat Kıvrak, Ahmet Ürkmez, Numan Doğu Güner, Sabahattin Aydın

Department of Urology, Tunceli State Hospital, Tunceli, Turkey. , Department of Urology, Fatih Sultan Mehmet Training and Research Hospital, İstanbul, Turkey. , Department of Urology, Dumlupınar University Faculty of Medicine, Kütahya, Turkey. , Department of Urology, Fatih Sultan Mehmet Training and Research Hospital, İstanbul, Turkey. , Department of Urology, Muş State Hospital, Muş, Turkey. , Department of Urology, Fatih Sultan Mehmet Training and Research Hospital, İstanbul, Turkey. , Department of Urology, Fatih Sultan Mehmet Training and Research Hospital, İstanbul, Turkey. , Department of Urology, İstanbul Medipol University, Istanbul, Turkey.

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