The connection between sleep patterns (sleep duration, trouble sleeping and sleep disorders) and benign prostatic hyperplasia, commonly referred to as BPH, is not yet clear. Our aim is to investigate the impact of sleep patterns on BPH risk in US men aged 40 and older.
We performed an observational analysis using data from NHANES 2005-2008 on males aged 40 and up, including a total of 2,555 participants. After accounting for confounding variables, we applied weighted multivariable logistic regression to assess the relationship between sleep patterns and BPH risk according to the complex multi-stage sampling design of NHANES.
In this study, 11.79% of the 2,555 American participants aged over 40 reported to have BPH. after adjusting for confounding variables, multivariable logistic regression analysis showed that short sleep duration, compared to healthy sleep duration (7-9 hours), was linked to a significantly higher risk of BPH (OR: 1.92, 95% CI: 1.42-2.41). Trouble sleeping and sleep disorder were also strongly associated with BPH. Moreover, there appears to be a stronger association among those with poor sleep patterns (OR: 2.07, 95% CI: 1.46-2.91).
Poor sleep patterns in men over 40 in the U.S. is significantly linked to a higher incidence of benign prostatic hyperplasia.
PloS one. 2025 Feb 25*** epublish ***
Dingliang Zhao, Junjie Han, Chengsen Lv, Jialin Gao
Department of Urology II, The First Hospital of Jilin University, Changchun, China., Department of Urology, The Second Hospital of Jilin University, Changchun, China.