The influence of metabolic syndrome and its components on the development of nephrolithiasis.

The prevalence of kidney stone disease is increasing, afflicting 7%-11% of the United States population. Multiple systemic conditions, including obesity and diabetes, are also on the rise. Further, the literature has demonstrated a strong association between metabolic syndrome, its components, and kidney stone disease. In this article, we aim to review the associations of metabolic syndrome and nephrolithiasis, discussing the pathophysiology, urinary parameters, and clinical presentations. With this knowledge, urologists will have a more comprehensive understanding of this complex population of metabolic stone formers enabling improved patient management and treatment of stone disease.

Asian journal of urology. 2018 Jun 08 [Epub]

Carter Boyd, Kyle Wood, Dustin Whitaker, Dean G Assimos

University of Alabama-Birmingham School of Medicine, Birmingham, AL, USA., Department of Urology, University of Alabama-Birmingham, Birmingham, AL, USA.