Oncological outcomes following robotic-assisted radical prostatectomy in a multiracial Asian population

This study evaluates the oncological outcomes of RARP in a multiracial Asian population from a single institution. All suitable patients from 1st January 2003-30th June 2013 were identified from a prospectively maintained cancer registry.

Peri-operative and oncological outcomes were analysed. Significance was defined as p < 0. 05. There were n = 725 patients identified with a mean follow-up duration 28 months. The mean operative time, EBL and LOS were 186 min, 215 ml and 3 days, respectively. The pathological stage was pT2 in 68. 6 % (n = 497/725), pT3 in 31. 3 % (n = 227/725) and n = 1 patient with pT4 disease. The pathological Gleason scores (GS) were 6 in 27. 9 % (n = 202/725), GS 7 in 63. 6 % (n = 461/725) and GS ≥ 8 in 8. 0 % (n = 58/725). The node positivity rate was 5. 8 % (n = 21/360). The positive margin rates were 31. 0 % (n = 154/497) and 70. 9 % (n = 161/227) for pT2 and pT3, respectively, and decreasing PSM rates are observed with surgical maturity. The biochemical recurrence rates were 9. 7 % (n = 48/497) and 34. 2 % (n = 78/228) for pT2 and pT3/T4, respectively. On multivariate analysis, independent predictors of BCR were pathological T stage and pathological Gleason score. Post-operatively, 78. 5 % (n = 569/725) of patients had no complications and 17. 7 % (n = 128/725) had minor (Clavien grade I-II) complications. This series, representing the largest from Southeast Asia, suggests that RARP can be a safe and oncologically feasible treatment for localised prostate cancer in an institution with moderate workload.

Journal of robotic surgery. 2015 Jul 07 [Epub]

Low Wei Xiang Alvin, Sim Hong Gee, Huang Hong Hong, Cheng Wai Sam Christopher, Ho Sien Sun Henry, Lau Kam On Weber, Tan Puay Hoon, Lee Lui Shiong

Department of Urology, Singapore General Hospital, Level 5, The Academia, 20 College Road, Singapore, 169856, Singapore. Department of Urology, Singapore General Hospital, Level 5, The Academia, 20 College Road, Singapore, 169856, Singapore. , Department of Urology, Singapore General Hospital, Level 5, The Academia, 20 College Road, Singapore, 169856, Singapore. , Department of Urology, Singapore General Hospital, Level 5, The Academia, 20 College Road, Singapore, 169856, Singapore. , Department of Urology, Singapore General Hospital, Level 5, The Academia, 20 College Road, Singapore, 169856, Singapore. , Department of Urology, Singapore General Hospital, Level 5, The Academia, 20 College Road, Singapore, 169856, Singapore. , Department of Pathology, Singapore General Hospital, Singapore, 169856, Singapore. , Department of Urology, Singapore General Hospital, Level 5, The Academia, 20 College Road, Singapore, 169856, Singapore. 

PubMed