Intrarenal pressure monitoring is emerging as an important tool in flexible ureteroscopy. Novel non-invasive intrarenal pressure monitoring devices are introduced. We evaluated the pressure readings simultaneously across four novel non-invasive intrarenal pressure monitoring devices against the urodynamic system.
Two IRP monitoring single-use flexible ureteroscopy: LithoVue Elite™ (Boston Scientific Corporation, Marlborough, MA, USA); ZebraScope™ (Happiness Works Medical Instruments Co., Ltd, Anhui, China); two intelligent intrarenal system integrated with irrigation and suction via flexible and navigable suction ureteral access sheath: i-MIMERsys™ (ZSR Biomedical Technology Co., Ltd, Dongguan, China); Tidor™ (YiGao Medical Technology Co., Ltd, Zhejiang, China) were tested against MMS/Laborie Nexam Pro Urodynamic System (Laborie Medical Technologies Corporation, Portsmouth, USA).
The degree of agreement between measurements from urodynamic system and the experimented device was demonstrated by Bland-Altman plots and intraclass correlation coefficients (ICCs). Compared to the urodynamic system, the average difference ± standard deviation of LithoVue Elite™ was 0.26 ± 1.75mmHg; ZebraScope™ 3.22 ± 1.86mHg, i-MIMERsys™ 0.96 ± 2.26mmhg; Tidor™ 1.09 ± 2.57mmHg. Pressure measured by LithoVue Elite™, ZebraScope™, i-MIMERsys™ and Tidor™ to urodynamic system showed excellent ICCs of 0.975 (p < 0.001), 0.915(p = 0.016), 0.955(p < 0.001) and 0.937(p < 0.001) respectively.
Pressure recordings from four novel non-invasive intrarenal monitoring devices, namely flexible ureteroscopes-LithoVue Elite™, ZebraScope™; and intelligent IRP monitoring systems via flexible and navigable suction ureteral access sheaths - i-MIMERsys™, Tidor™. were comparable to that of urodynamic system. This in-vitro study verifies that such non-invasive devices provide reliable data for monitoring intrarenal pressure changes.
World journal of urology. 2025 Jun 30*** epublish ***
Steffi Kar Kei Yuen, Zixiao Chen, Skyler Yuen, Alex Qinyang Liu, Chi-Ho Leung, Ivan Ching Ho Ko, Chi Kwok Chan, Bhaskar Somani, Thomas Herrmann, Helene Jung, Theodoros Tokas, Stefanie Croghan, Olivier Traxer, Peter Ka Fung Chiu, Ben Chew, Jeremy Yuen Chun Teoh, Vineet Gauhar, Zheng Li, Chi Fai Ng
S.H. Ho Urology Centre, Department of Surgery, The Chinese University of Hong Kong, Hong Kong, China., Multi-scale Medical Robotics Center, Chow Yuk Ho Technology Centre for Innovative Medicine, The Chinese University of Hong Kong, Hong Kong, China., Cheltenham Ladies College, Cheltenham, UK., European Association of Urology Section of Endourology (ESEUT), Arnhem, The Netherlands., Urological Research Center, Department of Urology, Vejle Hospital (a part of Lillebaelt Hospital), University Hospital of Southern Denmark, Vejle, Denmark., Department of Urology, Medical School, University General Hospital of Heraklion, University of Crete, Heraklion, Greece., Department of Surgery, Royal College of Surgeons in Ireland, Dublin, Ireland., Department of Urology, University of British Columbia, Vancouver, Canada., Department of Surgery, Multi-scale Medical Robotics Center, Chow Yuk Ho Technology Centre for Innovative Medicine, The Chinese University of Hong Kong, Hong Kong, China., S.H. Ho Urology Centre, Department of Surgery, The Chinese University of Hong Kong, Hong Kong, China. .