UroLift® is a minimally invasive treatment for patients with lower urinary tract symptoms secondary to benign prostatic hyperplasia. The primary objective was to evaluate the impact of UroLift® system treatment on quality of life. Secondary objectives assessed the impact on urinary symptoms and sexual function PATIENTS AND METHODS: Patients at 7 Spanish hospitals undergoing pharmacological treatment were offered the choice to continue this treatment or accept surgical intervention. The primary outcome, impact on quality of life, was assessed using the EuroQol-5D-5 L questionnaire. Secondary outcomes, including impact on symptoms, erectile function, and ejaculatory function, were evaluated using the IPSS, SHIM-5, and MSHQ-EjD-SF questionnaires, respectively. Outcomes were compared between groups.
91 patients chose UroLift®and 45 continued with pharmacotherapy. At 6 months, a positive impact on quality of life was estimated with UroLift®(0.046; SD: 0.02; p = 0.067), being significant in subgroups of patients aged >65 years (diff.: 0.034), PSA > 2.2 (diff.: 0.108), diabetes mellitus (diff.: 0.023), hypertension (diff.: 0.011) or hypercholesterolemia (diff.: 0.016). The impact on symptomatology was superior with UroLift®(-10.07; SD: 1.65; p < 0.001), being significant in subgroups aged >65 (diff.: 1.37), prostate >40 cc (diff.: 0.74), PSA > 2.2 (diff.: 2.63), and diabetes mellitus (diff.: 1.66), hypertension (diff.: 1.23). Erectile function was not affected (-0.33; SD: 1.99; p = 0.868) while ejaculatory function showed a favourable impact (2.98; SD: 1.26; p = 0.019).
Minimally invasive UroLift®system treatment is associated with a positive impact on quality of life and urinary symptoms without adversely affecting sexual function.
Actas urologicas espanolas. 2025 Feb 11 [Epub ahead of print]
C González Enguita, L López Martín, L M Herranz Fernández, B Sinues Ojas, C Barrera Rodríguez, J Extramiana Cameno, J Campá Bortoló, J M Oscá García, M Perán Teruel, V Gimeno Argente, A Navarro Beltrán, E López Alcina, I Povo Martín, Y Salvador Pallás Costa, A Budía Alba, J Ortiz Salvador, J J Salgado Plonski, P Suárez Sal, M Fernández Arjona
Servicio de Urología, Hospital Universitario Fundación Jiménez Díaz, Madrid, Spain., Servicio de Urología, Hospital de Henares, Madrid, Spain., Servicio de Urología, Hospital Universitario de Araba, Vitoria-Gasteiz, Spain., Servicio de Urología, Hospital Universitario Arnau de Vilanova, Valencia, Spain., Servicio de Urología, Hospital Universitario Arnau de Vilanova, Valencia, Spain. Electronic address: ., Servicio de Urología, Hospital General Universitario, Valencia, Spain., Servicio de Urología, Hospital Universitario La Fe, Valencia, Spain., Servicio de Urología, Hospital Universitario Cabueñes, Gijón, Asturias, Spain.