Initial outcomes and surgical techniques of prostatic urethral lift for benign prostatic hyperplasia in Japan.

The prostatic urethral lift (PUL) has been used as a minimally invasive surgery for benign prostatic hyperplasia (BPH) since April 2022 in Japan. This study evaluated the initial outcomes and surgical techniques of PUL for BPH.

In this prospective, single-center study, indications were based on the proper use guidelines for PUL in Japan. Preoperative patient status, postoperative progress at 1 and 3 months, and perioperative complications were evaluated. The surgical technique was changed twice, and the subgroup analysis and technique were evaluated.

Of the 50 patients who underwent surgeries performed by a single surgeon, the median age and prostate volume were 71 years and 42.0 mL, respectively. Furthermore, the median operative time and number of implants used were 20 min and 5, respectively. No postoperative fever or severe hematuria requiring reoperation occurred. All patients were discharged from the hospital the day following the PUL, as scheduled. Postoperative International Prostate Symptom Score, quality of life score, maximum flow rate, and postvoid residual volume at 1 and 3 months were significantly improved compared with the preoperative values. A significant improvement in maximum flow rate was observed in the subgroup analysis from 1 month postoperatively in the group with an anterior channel creation focus.

PUL is effective and safe in cases with prostate volumes of <100 mL. Lifting the bladder neck is important for opening an anterior prostatic urethral channel and improving urinary function during the early postoperative period.

International journal of urology : official journal of the Japanese Urological Association. 2024 Apr 16 [Epub ahead of print]

Go Anan, Kanya Kaga, Yosuke Fujishima, Hidero Minami, Thomas Mueller, David Sussman

Department of Urology, Yotsuya Medical Cube, Tokyo, Japan., Department of Urology, Chiba Prefectural Sawara Hospital, Chiba, Japan., Department of Urology, Iwate Prefectural Iwai Hospital, Iwate, Japan., Department of Urology, Tsurugi Hospital, Ishikawa, Japan., Department of Urology, Summit Health, Berkeley Heights, New Jersey, USA.