Oncologic outcomes in 408 consecutive patient cohort treated with da Vinci robot-assisted radical prostatectomy.

The objective of this study is to evaluate the general characteristics and oncological results in a cohort of 408 cases submitted to da Vinci Standard 4-armed robot-assisted radical prostatectomy (RARP), performed between October 2006 and February 2015 at Clínico San Carlos hospital. Statistical analysis was performed with the SPSS 20.0 program. Qualitative variables are presented with their frequency distribution and quantitative variables with their mean and standard deviation or median and interquartile range. The χ2 test was used to analyze the association of qualitative variables. The disease-free survival outcome variable was evaluated with a Kaplan-Meier curve analysis, and the differences were contrasted with the Breslow test. A Cox regression model was adjusted. Among the results, we highlight the follow-up of 47 months (32-68.75m), recurrence-free survival of 90 months (95% CI, 86-94), median time to recurrence of 23 months (10.5-37 m), recurrence 16'6% (68/408), biochemical recurrence (62/498, 15'2%) and 22% of complications, mostly Clavien I-II. The results are summarized in Tables 1 to 7 and Figure 1. CONCLUSIONS: 1) RARP is a safe technique with an acceptable percentage of complications, mostly minor (Clavien grades iandii), 2) We found a higher probability of remaining recurrence-free in the lower grades of the ISUP classification and a higher probability of recurrence in high-risk cases, and 3) The multivariate model showed that the ISUP grade was significantly related to survival and the ISUP and PSM classification grades were independent prognostic variables.

Actas urologicas espanolas. 2020 Mar 06 [Epub ahead of print]

J Moreno-Sierra, M I Galante-Romo, J L Senovilla-Perez, E Redondo-Gonzalez, I Galindo-Herrero, J Barrera-Ortega, R Vives-Dilmes, J Ariño-Irujo, L Fernández-Montarroso, C Fernandez Perez

Servicio de Urologia, Instituto de Investigación Sanitaria, Hospital Clínico San Carlos; Facultad de Médicina, Universidad Complutense, Madrid, España. Electronic address: ., Servicio de Urologia, Instituto de Investigación Sanitaria, Hospital Clínico San Carlos; Facultad de Médicina, Universidad Complutense, Madrid, España., Servicio de Diagnóstico por Imagen, Instituto de Investigación Sanitaria, Hospital Clínico San Carlos; Facultad de Medicina, Universidad Complutense, Madrid, España., Servicio de Anestesiología y Reanimación, Instituto de Investigación Sanitaria, Hospital Clínico San Carlos; Facultad de Medicina, Universidad Complutense, Madrid, España., Unidad de Apoyo a la Investigación, Servicio de Medicina Preventiva, Instituto de Investigación Sanitaria, Hospital Clínico San Carlos; Facultad de Medicina, Universidad Complutense, Madrid, España.