Kidney Cancer Weekly

April 27, 2026

Videos

Peer-to-Peer Clinical Conversations

Whole-Genome Sequencing-Based MRD Detection Under Study in Resectable Renal Cell Carcinoma - Taigo Kato

Taigo Kato discusses a longitudinal ctDNA study in renal cell carcinoma patients undergoing radical nephrectomy.

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Neoadjuvant Pembrolizumab and Radiotherapy for Kidney Cancer - Muhammad Ali

Leslie Ballas speaks with Muhammad Ali about the NAPSTER trial, a phase two randomized study examining neoadjuvant stereotactic radiotherapy with or without pembrolizumab prior to nephrectomy for renal cell carcinoma.

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Beyond the Abstracts

Pattern of Disease Recurrence and Outcomes after Progression of High-Risk Renal Cell Carcinoma (RCC) Patients Treated with Adjuvant Immunotherapy - Beyond the Abstract

End-of-Life and Palliative Care in Patients with Metastatic Renal Cancer - Beyond the Abstract

Conference Coverage

EAU 2026: Adjuvant Pembrolizumab + Belzutifan for Clear Cell RCC: Primary and Exploratory Efficacy Outcomes from the Phase 3 LITESPARK-022 Study

SES AUA 2026: Impact of Cytoreductive Nephrectomy for RCC with Tumor Thrombus: Results from the Intercontinental Collaboration of RCC

ASCO GU 2026: Discussant: Prevention to Progression – Targeting Foundational Biology in RCC

ASCO GU 2026: Phase 1b/2 KEYMAKER-U03 Substudy 03C of Belzutifan + Zanzalintinib or Belzutifan Monotherapy for Recurrent Clear Cell RCC During or After Anti-PD-(L)1 Therapy

SUO 2025: Relief of Venous Congestion as a Modifiable Cause of Renal Dysfunction in RCC with IVC Tumor Thrombus: A Comparative Cohort Study

Articles

Editor Selected Abstracts and Commentaries

Renal Cancer

Real-world comparison of the effectiveness and safety of immune-based combinations in elderly patients with advanced renal cell carcinoma (ARON-1 study).

Outcomes of immune-checkpoint inhibitor rechallenge in metastatic clear-cell renal cell carcinoma: results from a global real-world evidence study.

Clinical trial protocol of PODRACING: A randomized controlled trial evaluating 3D perfusion zone models for selective arterial clamping during robot-assisted partial nephrectomy.

Uncertainty-aware AI for tumor subtyping with histology and immunohistochemistry: A multi-center study in Renal Cell Carcinoma.

Racial/ethnic differences in time to nephrectomy and its association with cancer-specific mortality in localized renal cell carcinoma.

Genetic landscape and functional exploration of kidney cancer predisposition in cross-ancestral populations.

Prognostic and Predictive Value of the Clearseq1-4 Tumor Microenvironment Classification in Localized and Metastatic Clear-Cell Renal Cell Carcinoma.

Automation of four nephrometry scores using 3D models in renal cell carcinoma.

Kidney-specific HIF-1α-dependent ARL10/miR-1271-5p overexpression in clear cell renal cell carcinoma.

Laparoscopic Partial Nephrectomy Versus Microwave Ablation in the Treatment of Renal Masses.

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