Kidney Cancer Weekly

November 10, 2025

Videos

Peer-to-Peer Clinical Conversations

Study Examines CAIX-PET Imaging for Small Renal Mass Characterization - Timothy McClure

Timothy McClure

Zachary Klaassen speaks with Timothy McClure to discuss CAIX-PET imaging for small renal masses.

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Feasibility of Using an RNA-Seq Biomarker to Assign Therapy in the OPTIC RCC Trial - Pedro Barata

Pedro Barata

Pedro Barata discusses the OPTIC RCC trial, which uses RNA-sequencing biomarkers to guide treatment selection in metastatic clear cell renal cell carcinoma.

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Beyond the Abstracts

Vigorous Physical Activity as a Potential Environmental Risk Factor in Renal Medullary Carcinoma - Beyond the Abstract

Radiogenomic Correlation of Hypoxia-Related Biomarkers in Clear Cell Renal Cell Carcinoma - Beyond the Abstract

Conference Coverage

ESMO 2025: First-line Pembrolizumab-based Regimens for Advanced Clear Cell Renal Cell Carcinoma: KEYMAKER-U03 Substudy 03A

ESMO 2025: LenCabo: A Randomized Phase II Multicenter Trial of Lenvatinib plus Everolimus versus Cabozantinib in Patients with Metastatic Clear Cell RCC that Progressed on PD-1 Immune Checkpoint Inhibition

ESMO 2025: Kidney Cancer Discussant: Can we Combine More in Line 1 and Line 2?

ESMO 2025: Invited Discussant: KEYMAKER-UO3 Substudy 03A, LenCabo, & OPTIC RCC

ESMO 2025: Final Analysis of Lenvatinib + Pembrolizumab versus Sunitinib in Patients with Advanced RCC with or Without Bone Metastases in CLEAR

Articles

Editor Selected Abstracts and Commentaries

Renal Cancer

Impact of Hemoglobin A1c on the Obesity Paradox and Survival in Patients With Non-Metastatic Renal Cell Carcinoma.

PSMA PET/CT Incidental Detection of Tumor Thrombus From Unsuspected Renal Cell Carcinoma and Comparison with FDG PET/CT.

Genomic and Epigenomic Signatures Can Distinguish Aggressive Chromophobe Renal Cell Carcinoma from Indolent Renal Oncocytic Tumors in Clinical-grade Samples.

Sarcomatoid dedifferentiation as a predictor of overall mortality in surgically treated metastatic renal cell carcinoma.

Head-to-head comparison of TKI and CPI first-line treatment strategies in advanced renal cell carcinoma-Real-world data from the German research platform CARAT.

Lower SYNJ2BP Gene Expression Is Associated With Poor Survival Outcome and Treatment Response in Clear Cell Renal Cell Carcinoma: A Bioinformatics Analysis.

HIF2α inhibits glutaminase clustering in mitochondria to sustain growth of clear cell Renal Cell Carcinoma.

Sarcomatoid Differentiation in Renal Cell Carcinoma: Clinical and Pathologic Heterogeneity and Outcomes With Immune Checkpoint Inhibitors-Data From the ARON-1 Study.

Real-life Use of Cabozantinib in Front-line therapy for Metastatic Renal Cell Carcinoma: The CabFRONT Study (Meet-URO 24).

Impact of deep learning on CT-based organ-at-risk delineation for flank irradiation in paediatric renal tumours: a SIOP-RTSG radiotherapy committee study.

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